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干细胞分离、培养、分化和表征

Bio-Techne 为干细胞研究从分离和培养到确认、重新编程、分化以及表征的所有阶段提供支持。我们为细胞分离,针对细胞标记物表达、免疫分析、干细胞分化和单细胞分析的多色流式细胞术提供经优化和可重现的试剂盒。我们的优质试剂包括细胞因子和生长因子、细胞外基质蛋白、小分子、抗体、抗体组合和专用细胞培养基。

ES iPSC - Embryonic and Induced Pluripotent Stem Cell Embryonic Fibroblasts, Media, and Marker Panels

胚胎干细胞和诱导性多能干细胞

我们为您开展胚胎干细胞 (ES) 和诱导性多能干细胞 (iPSC) 研究提供众多工具,包括辐照小鼠胚胎成纤维细胞、小鼠胚胎成纤维细胞条件培养基、抗体标志物组合和培养基补充剂。

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类器官和 3D 培养

生成功能性组织样类器官和球状体,并进行毒理学检测。我们的方案和组织特异性配方涵盖优化的基础培养基试剂、基质组分、生长因子和小分子。

造血干细胞

利用我们的专用培养基和补充剂、谱系耗竭抗体组合、多色流式细胞分析试剂盒和集落形成细胞分析试剂研究造血干细胞 (HSC) 的分化。

间充质干细胞

浏览支持间充质干细胞 (MSC) 研究的试剂盒和试剂,包括用于成骨谱系、成脂谱系和成软骨谱系的优化基础培养基和补充剂,以及谱系诱导试剂和功能鉴定试剂盒。

神经干细胞

我们的神经干细胞 (NSC) 产品目录包括皮质干细胞、优化的培养补充剂、神经元和少突胶质细胞的分化试剂盒、功能鉴定试剂盒、成像染料和笼状化合物。

癌症干细胞

在研究组织特异性癌症干细胞的功能方面,我们提供癌症干细胞 (CSC) 鉴定试剂盒和抗体、CSC 群分离试剂盒、肿瘤球状体试验和优化培养基,以及细胞迁移和侵袭实验。

Why Use Bio-Techne Reagents for Culturing Stem Cells?

Our mission is to facilitate discovery and translation by ensuring high performance and lot-to-lot consistency of our products. Consistency is key to minimizing variability and standardizing protocols.

Don’t take it from us, listen as Stem Cell Core Facility Directors describe why they prefer Bio-Techne proteins and small molecules for their cultures!

Testimonial on the reliability of R&D Systems reagents for stem cell culture.

Featured Products

Cultrex Basement Membrane Extracts 350x210

Cultrex™ UltiMatrix RGF Basement Membrane Extract

  • Designed for organoid and stem cell culture
  • Protein composition and tensile strength optimized for 3D applications
  • Qualified for dome formation
Immunocytochemistry image of TRA-1-60 in iPSC

ExCellerate™ iPSC Expansion Medium

  • Animal component-free
  • Complete formulation – no growth factor supplementation required
  • Stable over long term culture

Coming Soon

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Animal-Free GMP BMP‑4

  • Equivalent bioactivity to our other BMP-4 proteins
  • Animal-free for clinical manufacturing processes
  • Backed by our quality standards and facility certifications. See GMP Capabilities

Custom Services for Stem Cell Research

The multitude of potential stem cell preparations and applications means that the exact product you need for your research may not be available. If you can’t find what you need, our expert scientists and custom services team are here to help. We will work with you to deliver reagents and assays to meet your requirements. Whether it’s as simple as a change in formulation or a completely new product, take advantage of our resources and expertise to overcome your challenge.

Inquire About Custom Services

Streamlining Translation for Regenerative Medicine

When it’s time to advance your regenerative medicine product to clinical manufacturing, partner with us for reliability, quality, and custom services. We will work with you to provide reproducible production of reagents and assays at clinical scale, with complete documentation. We offer GMP reagents as well as 21 CFR Part 11-compliant analytical instruments for automation and high throughput. We’re committed to helping you streamline the manufacture of regenerative medicine products.

Learn About Our GMP Capabilities
About Stem Cells

The defining characteristics of stem cells, i.e. their ability to self-renew and differentiate, make them a valuable resource in medical research and therapy. Directed differentiation of stem cells can provide insights into embryonic development, generate organ-like structures (organoids), and help us understand complex disease processes.

Stem cells are unspecialized cells that are capable of self-renewal through mitotic cell division, even after long periods of inactivity. Stem cell differentiation gives rise to the endoderm, ectoderm, and mesoderm germ layers which develop into the specialized cells of a tissues and organs.

Embryonic stem cells (ESCs) are found in the inner cell mass of blastocysts, adult (or somatic) stem cells maintain the populations of specific cell types, induced pluripotent stem cells (iPSCs) are produced by the reprogramming of somatic cells, and cancer stem cells (CSCs) reside in tissues where they give rise to local tumors. Hematopoietic stem cells (HSC) differentiate into the myeloid and lymphoid immune cell lineages. Multipotent mesenchymal stem cells (MSC) give rise to adipocytes, chondrocytes, osteocytes, and cardiomyocytes. Neural stem cells (NSC) can differentiate into neurons, astrocytes, and oligodendrocytes.

Owing to their tissue regenerative potential, stem cells can be utilized to repair or replace old or damaged cells, and this property is valuable in regenerative medicine. Stem cells offer the potential for treating many diseases including cancer, neurodegeneration, musculoskeletal disorders, heart disease, and diabetes. 3-dimensional cultures and organoids based on differentiated stem cells reproduce some functions of native tissues and are valuable for toxicology studies and drug discovery.