Webinar: Secrets of iCE Method Design for Protein Therapeutics
Isoelectric Focusing (IEF) has proven to be a powerful tool for determination of charge heterogeneity of therapeutic proteins. Since its introduction, iCE has become the preferred method for charge heterogeneity analysis by the biopharmaceutical industry, generating critical data for regulatory submissions and manufacturing lot releases. Presented in this seminar are analyte and instrument-based considerations crucial to achieving the maximum performance on the iCE. By reviewing the fundamentals of isoelectric focusing and the critical parameters in developing robust separations, the presenters will provide a step-by-step guide for optimizing separations.
Dr. Jiaqi Wu, Principal Scientist, ProteinSimple
Scott Mack, Field Applications Scientist, ProteinSimple