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Webinar: Method Development and Transfer with iCE: A QC Experience

Webinar Summary

Determination of isoelectric points and charge isoforms are critical steps in protein characterization for biopharmaceutical and vaccine development. Charge variants or heterogeneity commonly occurs as a result of post-translational modification including glycosylation, deamidation, sialylation and oxidation. These changes can affect biological activity and drug stability. In this webinar, we will present examples of method development and transfer for Charge heterogeneity analysis of biopharmaceutical products using iCE platform focusing on specific requirement of a QC environment. We will also provide a brief overview on robust method development on iCE3.



Joan Garrison, Scientist, QC Method Transfer, Cook Pharmica LLC

Scott Mack, Senior Scientist, ProteinSimple