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Validating Targets for Targeted Protein Degradation Using dTAG - A Comprehensive Workflow Solution

Life Science Posters

Life Science Posters Summary

Here we show two case studies illustrating the Bio-Techne dTAG workflow. We present data to demonstrate the value of testing both CRBN- and VHL-recruiting dTAG Degraders for each POI target as well as the use of negative control Degraders. We also show the utility of using a FKBP12 antibody for detecting POI dTAG fusion molecules, allowing for a more simplified procedure when probing multiple targets.

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