Huntington's disease (HD) is a severe monogenic neurodegenerative disorder. It is caused by a defect in the huntingtin gene and is characterized by the prevalent loss of GABAergic medium spiny neurons (MSN) in the striatum.
This poster summarizes the genetic and clinical manifestations of HD, brain pathology, molecular events in neurons, therapeutic strategies, and the use of iPSCs for HD modeling.
Which Brands are Currently Available on bio‑techne.com? R&D Systems, Tocris Bioscience and ProteinSimple branded products are available to purchase through bio‑techne.com. ProteinSimple branded instruments are available to quote. ACD branded products will be available on bio‑techne.com in the near future. Novus Biologicals branded products are not currently available on bio‑techne.com and can be found at novusbio.com.
Setting the standard in quality research reagents for over 30 years
A trusted leader in quality life science reagents
Your trusted supplier for innovative and high performance life science reagents
Proprietary systems and consumables for simpler, more quantitative and affordable protein analysis
Proprietary RNAscope® technology capable of detecting and quantifying RNA biomarkers in situ at single molecule sensitivity
A world leader in developing liquid biopsy based diagnostics
Sign In / Register