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Huntington's Disease: Pathophysiology and Clinical Prospects

Life Science Posters

Huntington's disease (HD) is a severe monogenic neurodegenerative disorder. It is caused by a defect in the huntingtin gene and is characterized by the prevalent loss of GABAergic medium spiny neurons (MSN) in the striatum.

This poster summarizes the genetic and clinical manifestations of HD, brain pathology, molecular events in neurons, therapeutic strategies, and the use of iPSCs for HD modeling.

Huntington's disease research poster, pathophysiology, genetics huntingtin functions and therapeutic strategies