Huntington's Disease: Pathophysiology and Clinical Prospects
Life Science PostersLife Science Posters Summary

Huntington's disease (HD) is a severe monogenic neurodegenerative disorder. It is caused by a defect in the huntingtin gene and is characterized by the prevalent loss of GABAergic medium spiny neurons (MSN) in the striatum.
This poster summarizes the genetic and clinical manifestations of HD, brain pathology, molecular events in neurons, therapeutic strategies, and the use of iPSCs for HD modeling.
Request Literature
To access this literature content please fill out the form below.