Finding Answers using Multiplex and Single Analyte Analysis

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Analyzing Crohn’s Disease Biomarkers with Immunoassays

Application Note:
Analyzing Crohn’s Disease Biomarkers with Immunoassays from Multiplex Discovery on Luminex to Single Analyte Analysis with Quantikine ELISA Kits

Multiple clinical biomarkers of Crohn’s Disease have been studied and developed into tests like serum C-Reactive Protein (CRP) and fecal calprotectin (FCP). Although there have been some studies to correlate biomarkers with endoscopic scores, relapses, and postoperative recurrence prediction, their main value thus far is in managing patients with Crohn’s disease. Therefore, identifying novel, accurate circulating biomarkers is a research priority.

This application note takes you through a proof-of-concept example of how to streamline your biomarker studies.

  • Biomarker discovery – using multiplexing
  • Validating results – using singleplex analysis with Quantikine ELISA kits
  • Analyte profiles in Crohn’s disease