Application Brief 1039: Acetylation NanoPro Assay

Acetylation is a common post-translation modification typically observed on chromatin proteins as well as other regulatory proteins and metabolic enzymes. The reaction is catalyzed by N-terminal acetyltransferases, occurs predominantly during protein synthesis and appears to be irreversible. Pan-Ac-Lysine antibodies are widely used for detection of acetylation of imunoprecipitated proteins when no specific antibodies are available.