VAL101 |
Number | Title | Journal | Species | Sample Types |
1 | Understanding the molecular pathway of triclosan-induced ADHD-like behavior: Involvement of the hnRNPA1-PKM2-STAT3 feedback loop | Environ Int. 2024 Sep:191:108966 | Human | Cell culture supernatant |
2 | Hypermethylation of the glutathione peroxidase 4 promoter predicts poor prognosis in patients with hepatitis B virus-associated acute-on-chronic liver failure | Front Mol Biosci. 2024 Jul 25:11:1421597 | Human | serum | |
3 | DNA of neutrophil extracellular traps promote NF-κB-dependent autoimmunity via cGAS/TLR9 in chronic obstructive pulmonary disease | Signal Transduct Target Ther. 2024 Jun 17;9(1):163 | Human | Cell culture supernatant |
4 | Hypermethylation of the glutathione peroxidase 4 gene promoter is associated with the occurrence of immune tolerance phase in chronic hepatitis B | Virol J. 2024 Mar 21;21(1):72 | Human | serum | |
5 | Upregulation of CD39 During Gout Attacks Promotes Spontaneous Remission of Acute Gouty Inflammation | Inflammation.2024 Apr;47(2):664-677 | Human | Cell culture supernatant |
6 | Carfilzomib modulates tumor microenvironment to potentiate immune checkpoint therapy for cancer | EMBO Mol Med. 2022 Jan 11;14(1):e14502 | Human | Cell culture supernatants |
7 | Two new 7, 20-epoxy- ent-kauranes from the aerial parts of Isodon eriocalyx | Nat Prod Res. 2021 Nov;35(21):3859-3864 | Human | cell supernatant |
8 | SFTSV Infection Induced Interleukin-1β Secretion Through NLRP3 Inflammasome Activation | Front Immunol. 2021 Feb 23;12:595140 | Human | cell supernatant |
9 | IL-1/IL-1R signaling induced by all-trans-retinal contributes to complement alternative pathway activation in retinal pigment epithelium | J Cell Physiol. 2021 May;236(5):3660-3674 | Human | Cell culture supernatants |
10 | Illuminating NAD+ Metabolism in Live Cells and In Vivo Using a Genetically Encoded Fluorescent Sensor | Autophagy. 2021 Oct;17(10):3011-3029 | Human | serum, cell culture supernatants |
11 | The Role of Caspase-4 and NLRP1 in MCF7 Cell Pyroptosis Induced by hUCMSC-Secreted Factors | Stem Cells Int. 2020 Jul 9;2020:8867115 | Human | Cell culture supernatants |
12 | Fine Particulate Matter (PM2.5) upregulates expression of Inflammasome NLRP1 via ROS/NF-κB signaling in HaCaT Cells | Int J Med Sci. 2020 Sep1;17(14):2200-2206 | Human | Cell culture supernatants |
13 | Circulatory CD4-Positive T-Lymphocyte Imbalance Mediated by Homocysteine-Induced AIM2 and NLRP1 Inflammasome Upregulation and Activation Is Associated with Human Abdominal Aortic Aneurysm | J Vasc Res. 2020;57(5):276-290 | Human | cell supernatant |
14 | MiR-297 alleviates LPS-induced A549 cell and mice lung injury via targeting cyclin dependent kinase 8 | Int Immunopharmacol. 2020 Mar;80:106197 | Human | Cell culture supernatants |
15 | microRNA-21 Aggravates Lipopolysaccharide-Induced Inflammation in MH7A Cells Through Targeting SNF5 | Inflammation. 2020 Apr;43(2):441-454 | Human | Cell culture supernatants |
16 | Application of cell-based biological bioassays for health risk assessment of PM2.5 exposure in three megacities, China | Environ Int. 2020 Jun;139:105703 | Human | Cell culture supernatants |
16 | 7-Ketocholesterol disturbs RPE cells phagocytosis of the outer segment of photoreceptor and induces inflammation through ERK signaling pathway | Exp Eye Res. 2019 Dec;189:107849 | Human | cell media | |
17 | Retinal Pigment Epithelium Cell Death Is Associated With NLRP3 Inflammasome Activation by All-trans Retinal | Invest Ophthalmol Vis Sci. 2019 Jul 1;60(8):3034-3045 | Human | Cell culture supernatants |
18 | Profiling and functional characterization of circulation LncRNAs that are associated with coronary atherosclerotic plaque stability | Am J Transl Res. 2019 Jun 15;11(6):3801-3815 | Human | Cell culture supernatants |
19 | NOD1 modulates decidual stromal cell function to maintain pregnancy in the early trimester | Cell Biochem Funct. 2019 Oct;37(7):464-473 | Human | Cell culture supernatants |
20 | Downregulation of GSDMD attenuates tumor proliferation via the intrinsic mitochondrial apoptotic pathway and inhibition of EGFR/Akt signaling and predicts a good prognosis in non‑small cell lung cancer | Oncol Rep. 2018 Oct;40(4):1971-1984 | Human | Cell culture supernatants |
21 | Cytokine Secretion and Pyroptosis of Thyroid Follicular Cells Mediated by Enhanced NLRP3, NLRP1, NLRC4, and AIM2 Inflammasomes Are Associated With Autoimmune Thyroiditis | Front Immunol. 2018 Jun 4;9:1197 | Human | cell supernatant |
22 | Pyroptosis of MCF7 Cells Induced by the Secreted Factors of hUCMSCs | Stem Cells Int. 2018 Nov 11;2018:5912194 | Human | Cell culture supernatants |
23 | Megalin/Cubulin-Lysosome-mediated Albumin Reabsorption Is Involved in the Tubular Cell Activation of NLRP3 Inflammasome and Tubulointerstitial Inflammation | J Biol Chem. 2015 Jul 17;290(29):18018-18028 | Human | Cell culture supernatants |
24 | Inhibition of STAT5a by Naa10p contributes to decreased breast cancer metastasis | Carcinogenesis. 2014 Oct;35(10):2244-53 | Human | Cell culture supernatants |
25 | Induction of heme oxygenase-1 attenuates lipopolysaccharide-induced inflammasome activation in human gingival epithelial cells | Int J Mol Med. 2014 Oct;34(4):1039-44 | Human | Cell culture medium |
26 | Expression and functional characterization of NOD2 in decidual stromal cells isolated during the first trimester of pregnancy | PLoS One. 2014 Jun 16;9(6):e99612 | Human | Cell culture supernatants |
27 | Tumor-associated macrophages induce lymphangiogenesis in cervical cancer via interaction with tumor cells | APMIS.2014 Nov;122(11):1059-69 | Human | Cell culture supernatants |
28 | Activation of the Nlrp3 inflammasome by mitochondrial reactive oxygen species: a novel mechanism of albumin-induced tubulointerstitial inflammation | Int J Biochem Cell Biol. 2014 Dec;57:7-19 | Human | Cell culture supernatants |
VAL102C | | | | |
Number | Title | Journal | Species | Sample Types |
1 | Association analysis of MTHFR (rs1801133 and rs1801131) gene polymorphism towards the development of type 2 diabetes mellitus in Dali area population from Yunnan Province, China | PeerJ. 2024 Oct 24:12:e18334 | Human | serum | |
2 | Understanding the molecular pathway of triclosan-induced ADHD-like behavior: Involvement of the hnRNPA1-PKM2-STAT3 feedback loop | Environ Int. 2024 Sep:191:108966 | Human | Cell culture supernatants |
3 | Hypermethylation of the glutathione peroxidase 4 promoter predicts poor prognosis in patients with hepatitis B virus-associated acute-on-chronic liver failure | Front Mol Biosci. 2024 Jul 25:11:1421597 | Human | serum | |
4 | Metochalcone induces senescence-associated secretory phenotype via JAK2/STAT3 pathway in breast cancer | Oncol Res. 2024 Apr 23;32(5):943-953 | Human | Cell culture supernatants |
5 | Hypermethylation of the glutathione peroxidase 4 gene promoter is associated with the occurrence of immune tolerance phase in chronic hepatitis B | Virol J. 2024 Mar 21;21(1):72 | Human | serum | |
6 | Upregulation of CD39 During Gout Attacks Promotes Spontaneous Remission of Acute Gouty Inflammation | Inflammation. 2024 Apr;47(2):664-677 | Human | Cell culture supernatant |
7 | BR109, a Novel Fully Humanized T-Cell-Engaging Bispecific Antibody with GPRC5D Binding, Has Potent Antitumor Activities in Multiple Myeloma | Cancers (Basel). 2023 Dec 9;15(24):5774 | Human | Cell culture supernatants |
8 | Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis. | Cell Rep. 2023 Aug 29;42(8):112944. | Human | Cell culture supernatants |
9 | Sialylation of IgG inhibits the formation of galactose-deficient IgA1-containing immune complexes and protects mesangial cells from injury in IgA nephropathy | BMC Nephrol. 2022 Jan 11;23(1):25 | Human | Cell culture supernatants |
10 | RNA circles with minimized immunogenicity as potent PKR inhibitors | Mol Cell. 2022 Jan 20;82(2):420-434.e6 | Human | Cell culture supernatants |
11 | Reveals of quercetin's therapeutic effects on oral lichen planus based on network pharmacology approach and experimental validation | Sci Rep. 2022 Jan 21;12(1):1162 | Human | Cell culture supernatants |
12 | Phenformin Down-Regulates c-Myc Expression to Suppress the Expression of Pro-Inflammatory Cytokines in Keratinocytes | Cells. 2022 Aug 5;11(15):2429 | Human | Cell culture supernatants |
13 | SFTSV Infection Induced Interleukin-1β Secretion Through NLRP3 Inflammasome Activation | Front Immunol. 2021 Feb 23;12:595140 | Human | cell supernatant |
14 | Up-Regulation of Activating Transcription Factor 3 in Human Fibroblasts Inhibits Melanoma Cell Growth and Migration Through a Paracrine Pathway | Front Oncol. 2020 Apr 21;10:624 | Human | Cell culture medium |
15 | 1α,25-dihydroxyvitamin D3 promotes early osteogenic differentiation of PDLSCs and a 12-year follow-up case of early-onset vitamin D deficiency periodontitis | J Steroid Biochem Mol Biol. 2021 Apr;208:105805 | Human | Cell culture supernatants |
16 | CagA orchestrates eEF1A1 and PKCδ to induce interleukin-6 expression in Helicobacter pylori-infected gastric epithelial cells | Gut Pathog. 2020 Jul 3;12:31 | Human | Cell culture supernatants |
17 | Application of cell-based biological bioassays for health risk assessment of PM2.5 exposure in three megacities, China | Environ Int. 2020 Jun;139:105703 | Human | Cell culture supernatants |
18 | MiR-297 alleviates LPS-induced A549 cell and mice lung injury via targeting cyclin dependent kinase 8 | Int Immunopharmacol. 2020 Mar;80:106197 | Human | Cell culture supernatants |
19 | microRNA-21 Aggravates Lipopolysaccharide-Induced Inflammation in MH7A Cells Through Targeting SNF5 | Inflammation. 2020 Apr;43(2):441-454 | Human | Cell culture supernatants |
20 | Implication of inflammatory cytokines in the aqueous humour for management of macular diseases | Acta Ophthalmol. 2020 May;98(3):e309-e315 | Human | aqueous humor |
21 | Immunomodulation‐Based Strategy for Improving Soft Tissue and Metal Implant Integration and Its Implications in the Development of Metal Soft Tissue Materials | Adv Funct Mater. 2020 March 20 | Human | Cell culture supernatants |
22 | Circulating soluble receptor for advanced glycation end products and other factors in type 2 diabetes patients with colorectal cancer | BMC Endocr Disord.2020 Nov 13;20(1):170 | Human | serum | |
23 | Inflammatory cytokines in highly myopic eyes | Sci Rep. 2019 Mar 5;9(1):3517 | Human | aqueous humor |
24 | A novel tumor-promoting mechanism of IL6 and the therapeutic efficacy of tocilizumab: Hypoxia-induced IL6 is a potent autophagy initiator in glioblastoma via the p-STAT3-MIR155-3p-CREBRF pathway | Autophagy. 2016 Jul 2;12(7):1129-52 | Human | serum, cell culture supernatants |
25 | Methylation of suppressor of cytokine signaling 1 gene promoter is associated with acute-on-chronic hepatitis B liver failure | J Viral Hepat. 2015 Mar;22(3):307-17 | Human | plasma | |
26 | Histone acetylation regulates orphan nuclear receptor NR4A1 expression in hypercholesterolaemia | Clin Sci (Lond). 2015 Dec;129(12):1151-61 | Human | plasma, cell culture supernatants |
27 | Prognoses of patients with acute-on-chronic hepatitis B liver failure are closely associated with altered SOCS1 mRNA expression and cytokine production following glucocorticoid treatment | Cell Mol Immunol. 2014 Jul;11(4):396-404 | Human | Plasma | |
28 | Soluble interleukin-6 receptor-mediated innate immune response to DNA and RNA viruses | J Virol. 2013 Oct;87(20):11244-54 | Human | Cell culture supernatants |
VAL103 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | DNA of neutrophil extracellular traps promote NF-κB-dependent autoimmunity via cGAS/TLR9 in chronic obstructive pulmonary disease | Signal Transduct Target Ther. 2024 Jun 17;9(1):163 | Human | Cell culture supernatant |
2 | Changes in Serum Interleukin-8 Levels Predict Response to Immune Checkpoint Inhibitors Immunotherapy in Unresectable Hepatocellular Carcinoma Patients | J Inflamm Res. 2024 May 25:17:3397-3406 | Human | serum | |
3 | Metochalcone induces senescence-associated secretory phenotype via JAK2/STAT3 pathway in breast cancer | Oncol Res. 2024 Apr 23;32(5):943-953 | Human | Cell culture supernatants |
4 | Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis. | Cell Rep. 2023 Aug 29;42(8):112944 | Human | Cell culture supernatants |
5 | Phenformin Down-Regulates c-Myc Expression to Suppress the Expression of Pro-Inflammatory Cytokines in Keratinocytes | Cells. 2022 Aug 5;11(15):2429 | Human | Cell culture supernatants |
6 | Reversal of NADPH Oxidase-Dependent Early Oxidative and Inflammatory Responses in Chronic Obstructive Pulmonary Disease by Puerarin | Oxid Med Cell Longev. 2022 Apr 25;2022:5595781 | Human | Cell culture supernatants |
7 | Up-Regulation of Activating Transcription Factor 3 in Human Fibroblasts Inhibits Melanoma Cell Growth and Migration Through a Paracrine Pathway | Front Oncol. 2020 Apr 21;10:624 | Human | Cell culture medium |
8 | Probiotic effect on Helicobacter pylori attachment and inhibition of inflammation in human gastric epithelial cells | Exp Ther Med. 2019 Sep;18(3):1551-1562 | Human | Cell culture supernatants |
9 | Screening probiotics from Lactobacillus strains according to their abilities to inhibit pathogen adhesion and induction of pro-inflammatory cytokine IL-8 | J Dairy Sci. 2018 Jun;101(6):4822-4829 | Human | Cell culture supernatants |
10 | PKC/NADPH oxidase are involved in the protective effect of pioglitazone in high homocysteine-induced paracrine dyfunction in endothelial progenitor cells | Am J Transl Res. 2017 Mar 15;9(3):1037-1048 | Human | Cell culture supernatants |
11 | Membrane cholesterol plays an important role in enteropathogen adhesion and the activation of innate immunity via flagellin-TLR5 signaling | Arch Microbiol. 2015 Aug;197(6):797-803 | Human | Cell culture supernatants |
12 | Tumor-associated macrophages induce lymphangiogenesis in cervical cancer via interaction with tumor cells | APMIS.2014 Nov;122(11):1059-69 | Human | Cell culture supernatants |
VAL104C | | | | |
Number | Title | Journal | Species | Sample Types |
1 | BR109, a Novel Fully Humanized T-Cell-Engaging Bispecific Antibody with GPRC5D Binding, Has Potent Antitumor Activities in Multiple Myeloma | Cancers (Basel). 2023 Dec 9;15(24):5774 | Human | Cell culture supernatants |
2 | Cancer-cell-derived fumarate suppresses the anti-tumor capacity of CD8+ T cells in the tumor microenvironment | Cell Metab.2023 Jun 6;35(6):961-978.e10. | Human | Cell culture supernatants |
3 | Reveals of quercetin's therapeutic effects on oral lichen planus based on network pharmacology approach and experimental validation | Sci Rep. 2022 Jan 21;12(1):1162 | Human | Cell culture supernatants |
4 | TriBAFF-CAR-T cells eliminate B-cell malignancies with BAFFR-expression and CD19 antigen loss | Cancer Cell Int. 2021 Apr 17;21(1):223 | Human | Cell culture supernatants |
5 | High-throughput functional screening for next-generation cancer immunotherapy using droplet-based microfluidics | Sci Adv. 2021 Jun 11;7(24):eabe3839 | Human | cell supernatant |
6 | NOD1 modulates decidual stromal cell function to maintain pregnancy in the early trimester | Cell Biochem Funct. 2019 Oct;37(7):464-473 | Human | Cell culture supernatants |
7 | Optimized DNA electroporation for primary human T cell engineering | BMC Biotechnol. 2018 Jan 30;18(1):4 | Human | Cell culture supernatants |
8 | Abrasive Endoprosthetic Wear Particles Inhibit IFN-γ Secretion in Human Monocytes Via Upregulating TNF-α-Induced miR-29b | Inflammation. 2017 Feb;40(1):166-173 | Human | Cell culture supernatants |
9 | Characterization of the subsets of human NKT-like cells and the expression of Th1/Th2 cytokines in patients with unexplained recurrent spontaneous abortion | J Reprod Immunol. 2015 Aug;110:81-8 | Human | Cell culture medium |
10 | Methylation of suppressor of cytokine signaling 1 gene promoter is associated with acute-on-chronic hepatitis B liver failure | J Viral Hepat. 2015 Mar;22(3):307-17 | Human | plasma | |
11 | Expression and functional characterization of NOD2 in decidual stromal cells isolated during the first trimester of pregnancy | PLoS One. 2014 Jun 16;9(6):e99612 | Human | Cell culture supernatants |
VAL105G | | | | |
Number | Title | Journal | Species | Sample Types |
1 | Association analysis of MTHFR (rs1801133 and rs1801131) gene polymorphism towards the development of type 2 diabetes mellitus in Dali area population from Yunnan Province, China | PeerJ. 2024 Oct 24:12:e18334 | Human | serum | |
2 | Hypermethylation of the glutathione peroxidase 4 promoter predicts poor prognosis in patients with hepatitis B virus-associated acute-on-chronic liver failure | Front Mol Biosci. 2024 Jul 25:11:1421597 | Human | serum | |
3 | BR109, a Novel Fully Humanized T-Cell-Engaging Bispecific Antibody with GPRC5D Binding, Has Potent Antitumor Activities in Multiple Myeloma | Cancers (Basel). 2023 Dec 9;15(24):5774 | Human | Cell culture supernatants |
4 | Upregulation of CD39 During Gout Attacks Promotes Spontaneous Remission of Acute Gouty Inflammation | Inflammation. 2024 Apr;47(2):664-677 | Human | Cell culture supernatant |
5 | Z1456467176 alleviates gouty arthritis by allosterically modulating P2X7R to inhibit NLRP3 inflammasome activation | Front Pharmacol. 2022 Aug 16;13:979939 | Human | Cell culture supernatants |
6 | Withaphysalins from Medicinal and Edible Physalis minima and Their Anti-inflammatory Activities | J Agric Food Chem. 2022 May 11;70(18):5595-5609 | Human | Cell culture supernatants |
7 | Sialylation of IgG inhibits the formation of galactose-deficient IgA1-containing immune complexes and protects mesangial cells from injury in IgA nephropathy | BMC Nephrol. 2022 Jan 11;23(1):25 | Human | Cell culture supernatants |
8 | Phenformin Down-Regulates c-Myc Expression to Suppress the Expression of Pro-Inflammatory Cytokines in Keratinocytes | Cells. 2022 Aug 5;11(15):2429 | Human | Cell culture supernatants |
9 | Carfilzomib modulates tumor microenvironment to potentiate immune checkpoint therapy for cancer | EMBO Mol Med. 2022 Jan 11;14(1):e14502 | Human | Cell culture supernatants |
10 | SFTSV Infection Induced Interleukin-1β Secretion Through NLRP3 Inflammasome Activation | Front Immunol. 2021 Feb 23;12:595140 | Human | cell supernatant |
11 | MiR-24-3p attenuates IL-1β-induced chondrocyte injury associated with osteoarthritis by targeting BCL2L12 | J Orthop Surg Res. 2021 Jun 11;16(1):371 | Human | Cell culture supernatants |
12 | Immunomodulation‐Based Strategy for Improving Soft Tissue and Metal Implant Integration and Its Implications in the Development of Metal Soft Tissue Materials | Adv Funct Mater. 2020 March 20 | Human | Cell culture supernatants |
13 | Up-Regulation of Activating Transcription Factor 3 in Human Fibroblasts Inhibits Melanoma Cell Growth and Migration Through a Paracrine Pathway | Front Oncol. 2020 Apr 21;10:624 | Human | Cell culture medium |
14 | Tuning the surface immunomodulatory functions of polyetheretherketone for enhanced osseointegration | Biomaterials. 2020 Feb;230:119642 | Human | Cell culture supernatants |
15 | MiR-297 alleviates LPS-induced A549 cell and mice lung injury via targeting cyclin dependent kinase 8 | Int Immunopharmacol. 2020 Mar;80:106197 | Human | Cell culture supernatants |
16 | Application of cell-based biological bioassays for health risk assessment of PM2.5 exposure in three megacities, China | Environ Int. 2020 Jun;139:105703 | Human | Cell culture supernatants |
17 | Profiling and functional characterization of circulation LncRNAs that are associated with coronary atherosclerotic plaque stability | Am J Transl Res. 2019 Jun 15;11(6):3801-3815. eCollection 2019 | Human | Cell culture supernatants |
18 | NOD1 modulates decidual stromal cell function to maintain pregnancy in the early trimester | Cell Biochem Funct. 2019 Oct;37(7):464-473 | Human | Cell culture supernatants |
19 | Optimized DNA electroporation for primary human T cell engineering | BMC Biotechnol. 2018 Jan 30;18(1):4 | Human | Cell culture supernatants |
20 | Radiosensitization by CpG ODN7909 in an epidermoid laryngeal carcinoma Hep-2 cell line | J Int Med Res. 2017 Dec;45(6):2009-2022 | Human | Cell culture supernatants |
21 | Abrasive Endoprosthetic Wear Particles Inhibit IFN-γ Secretion in Human Monocytes Via Upregulating TNF-α-Induced miR-29b | Inflammation. 2017 Feb;40(1):166-173 | Human | Cell culture supernatants |
22 | Linker-free covalent immobilization of heparin, SDF-1α, and CD47 on PTFE surface for antithrombogenicity, endothelialization and anti-inflammation | Biomaterials. 2017 Sep;140:201-211 | Human | Cell culture supernatants |
23 | Knockdown of p54nrb inhibits migration, invasion and TNF-α release of human acute monocytic leukemia THP1 cells | Oncol Rep. 2016 Jun;35(6):3742-8 | Human | Cell culture supernatants |
24 | Methylation of suppressor of cytokine signaling 1 gene promoter is associated with acute-on-chronic hepatitis B liver failure | J Viral Hepat. 2015 Mar;22(3):307-17 | Human | plasma | |
25 | Membrane cholesterol plays an important role in enteropathogen adhesion and the activation of innate immunity via flagellin-TLR5 signaling | Arch Microbiol. 2015 Aug;197(6):797-803 | Human | Cell culture supernatants |
26 | Expression and functional characterization of NOD2 in decidual stromal cells isolated during the first trimester of pregnancy | PLoS One. 2014 Jun 16;9(6):e99612 | Human | Cell culture supernatants |
27 | Prognoses of patients with acute-on-chronic hepatitis B liver failure are closely associated with altered SOCS1 mRNA expression and cytokine production following glucocorticoid treatment | Cell Mol Immunol. 2014 Jul;11(4):396-404 | Human | plasma | |
VAL106 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | Identifying cancer cell-secreted proteins that activate cancer-associated fibroblasts as prognostic factors for patients with pancreatic cancer | J Cell Mol Med.2022 Nov;26(22):5657-5669. | Human | Cell culture supernatants |
2 | Deficiency of ribosomal proteins reshapes the transcriptional and translational landscape in human cells | Nucleic Acids Res. 2022 Jul 8;50(12):6601-6617 | Human | Cell culture supernatants |
3 | Hydrogel from acellular porcine adipose tissue promotes survival of adipose tissue transplantation | Biomed Mater. 2021 Apr 30;16(4) | Human | Cell culture medium |
4 | Cyclic tensile forces enhance the angiogenic properties of HUVECs by promoting the activities of human periodontal ligament cells | J Periodontol. 2021 Jan;92(1):159-169 | Human | Cell culture supernatants |
5 | Implication of inflammatory cytokines in the aqueous humour for management of macular diseases | Acta Ophthalmol. 2020 May;98(3):e309-e315 | Human | aqueous humor |
6 | Growth differentiation factor 9 inhibits vascular endothelial growth factor expression in human granulosa cells | Gynecol Endocrinol. 2020 Oct;36(10):907-911 | Human | Cell culture supernatants |
7 | The Caspase-3/PKCδ/Akt/VEGF-A Signaling Pathway Mediates Tumor Repopulation during Radiotherapy | Clin Cancer Res. 2019 Jun 15;25(12):3732-3743 | Human | Cell culture supernatants |
8 | Inflammatory cytokines in highly myopic eyes | Sci Rep. 2019 Mar 5;9(1):3517 | Human | aqueous humor |
9 | PKC/NADPH oxidase are involved in the protective effect of pioglitazone in high homocysteine-induced paracrine dyfunction in endothelial progenitor cells | Am J Transl Res. 2017 Mar 15;9(3):1037-1048 | Human | Cell culture supernatants |
10 | Dying glioma cells establish a proangiogenic microenvironment through a caspase 3 dependent mechanism | Cancer Lett. 2017 Jan 28;385:12-20 | Human | Cell culture supernatants |
11 | Caspase 3 in dying tumor cells mediates post-irradiation angiogenesis | Oncotarget. 2015 Oct 20;6(32):32353-67 | Human | Cell culture supernatants |
12 | 12-Deoxyphorbol 13-palmitate inhibits the expression of VEGF and HIF-1α in MCF-7 cells by blocking the PI3K/Akt/mTOR signaling pathway | Oncol Rep. 2015 Oct;34(4):1755-60 | Human | Cell culture medium |
VAL110 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | Low level of ARID1A contributes to adaptive immune resistance and sensitizes triple-negative breast cancer to immune checkpoint inhibitors | Cancer Commun (Lond). 2023 Sep;43(9):1003-1026. | Human | Cell culture supernatants |
2 | Histone Methyltransferase SETDB1 Promotes Immune Evasion in Colorectal Cancer via FOSB-Mediated Downregulation of MicroRNA-22 through BATF3/PD-L1 Pathway | J Immunol Res. 2022 Apr 20;2022:4012920 | Human | Cell culture supernatants |
3 | TriBAFF-CAR-T cells eliminate B-cell malignancies with BAFFR-expression and CD19 antigen loss | Cancer Cell Int. 2021 Apr 17;21(1):223 | Human | Cell culture supernatants |
4 | NPM1 upregulates the transcription of PD-L1 and suppresses T cell activity in triple-negative breast cancer | Nat Commun. 2020 Apr 3;11(1):1669 | Human | Cell culture supernatants |
5 | Caspase 3 in dying tumor cells mediates post-irradiation angiogenesis | J Exp Clin Cancer Res. 2018 Oct 29;37(1):261 | Human | Cell culture supernatants |
6 | Orai1 downregulation impairs lymphocyte function in type 2 diabetes mellitus | Biochem Biophys Res Commun. 2018 Jun 2;500(2):384-390 | Human | Cell culture supernatants |
7 | Optimized DNA electroporation for primary human T cell engineering | BMC Biotechnol. 2018 Jan 30;18(1):4 | Human | Cell culture supernatants |
VAL112 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | Creatine Kinase-MM/Proto-oncogene Tyrosine-Protein Kinase Receptor as a Sensitive Indicator for Duchenne Muscular Dystrophy Carriers | Mol Neurobiol. 2024 May 20. | Human | serum | |
2 | NOD1 modulates decidual stromal cell function to maintain pregnancy in the early trimester | Cell Biochem Funct. 2019 Oct;37(7):464-473 | Human | Cell culture supernatants |
3 | Characterization of the subsets of human NKT-like cells and the expression of Th1/Th2 cytokines in patients with unexplained recurrent spontaneous abortion | J Reprod Immunol. 2015 Aug;110:81-8 | Human | Cell culture medium |
4 | Expression and functional characterization of NOD2 in decidual stromal cells isolated during the first trimester of pregnancy | PLoS One. 2014 Jun 16;9(6):e99612 | Human | Cell culture supernatants |
VAL113 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | Chemically modified small interfering RNA targeting Hedgehog signaling pathway for rheumatoid arthritis therapy | Mol Ther Nucleic Acids. 2022 Dec 12:31:88-104. | Human | Cell culture supernatants |
2 | Profiling and functional characterization of circulating LncRNAs that are associated with coronary atherosclerotic plaque stability - PubMed (nih.gov) | Am J Transl Res. 2019 Jun 15;11(6):3801-3815. | Human | Cell culture supernatants |
VAL114 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | Postmortem biochemical analysis of soluble ST2 in the pericardial fluid of patients with sudden cardiac death caused by ischemic heart disease: a pilot study | Forensic Sci Med Pathol.2023 Jul 14. | Human | pericardial fluid |
2 | IL-33 promotes the progression of nonrheumatic aortic valve stenosis via inducing differential phenotypic transition in valvular interstitial cells - PubMed (nih.gov) | J Cardiol. 2020 Feb;75(2):124-133 | Human | plasma | |
VAL117 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | Circulating PD-L1 is associated with T cell infiltration and predicts prognosis in patients with CRLM following hepatic resection - PubMed (nih.gov) | Cancer Immunol Immunother. 2022 Mar;71(3):661-674 | Human | plasma, circulating exosomes |
VAL121 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | NOD1 modulates decidual stromal cell function to maintain pregnancy in the early trimester | Cell Biochem Funct. 2019 Oct;37(7):464-473 | Human | Cell culture supernatants |
2 | Radiosensitization by CpG ODN7909 in an epidermoid laryngeal carcinoma Hep-2 cell line | J Int Med Res. 2017 Dec;45(6):2009-2022 | Human | Cell culture supernatants |
3 | Expression and functional characterization of NOD2 in decidual stromal cells isolated during the first trimester of pregnancy | PLoS One. 2014 Jun 16;9(6):e99612 | Human | Cell culture supernatants |
VAL122 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | Competitive binding of transcription factors underlies flexibility of T peripheral helper cells and T follicular helper cells in SLE | Rheumatology (Oxford). 2022 Nov 2;61(11):4547-4557 | Human | serum | |
VAL123 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | A programmed surface on polyetheretherketone for sequentially dictating osteoimmunomodulation and bone regeneration to achieve ameliorative osseointegration under osteoporotic conditions | Bioact Mater. 2022 Feb 1;14:364-376 | Mouse | Cell culture supernatants |
2 | NOD1 modulates decidual stromal cell function to maintain pregnancy in the early trimester | Cell Biochem Funct. 2019 Oct;37(7):464-473 | Human | Cell culture supernatants |
3 | Characterization of the subsets of human NKT-like cells and the expression of Th1/Th2 cytokines in patients with unexplained recurrent spontaneous abortion | J Reprod Immunol. 2015 Aug;110:81-8 | Human | Cell culture medium |
4 | Expression and functional characterization of NOD2 in decidual stromal cells isolated during the first trimester of pregnancy | PLoS One. 2014 Jun 16;9(6):e99612 | Human | Cell culture supernatants |
VAL127 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | Enhancement of the function of mesenchymal stem cells by using a GMP-grade three-dimensional hypoxic large-scale production system | Heliyon. 2024 May 18;10(10):e30968 | Human | Cell culture supernatant |
2 | Metochalcone induces senescence-associated secretory phenotype via JAK2/STAT3 pathway in breast cancer | Oncol Res. 2024 Apr 23;32(5):943-953 | Human | Cell culture supernatants |
3 | Sialylation of IgG inhibits the formation of galactose-deficient IgA1-containing immune complexes and protects mesangial cells from injury in IgA nephropathy - PubMed (nih.gov) | BMC Nephrol. 2022 Jan 11;23(1):25 | Human | Cell culture supernatants |
VAL130 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | Bispecific CS1-BCMA CAR-T cells are clinically active in relapsed or refractory multiple myeloma | Leukemia. 2023 Oct 17. | Human | Bone marrow, Peripheral blood |
VAL131 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | Clinical Value of Serum Interleukin-18 in Neonatal Sepsis Diagnosis and Mortality Prediction | J Inflamm Res. 2022 Dec 30:15:6923-6930 | Human | serum | |
2 | MiR-24-3p attenuates IL-1β-induced chondrocyte injury associated with osteoarthritis by targeting BCL2L12 | J Orthop Surg Res. 2021 Jun 11;16(1):371 | Human | Cell culture supernatants |
3 | Megalin/Cubulin-Lysosome-mediated Albumin Reabsorption Is Involved in the Tubular Cell Activation of NLRP3 Inflammasome and Tubulointerstitial Inflammation | J Biol Chem. 2015 Jul 17;290(29):18018-18028 | Human | Cell culture supernatants |
4 | Activation of the Nlrp3 inflammasome by mitochondrial reactive oxygen species: a novel mechanism of albumin-induced tubulointerstitial inflammation | Int J Biochem Cell Biol. 2014 Dec;57:7-19 | Human | Cell culture supernatants |
VAL134 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | FSTL3 is highly expressed in adipose tissue of individuals with overweight or obesity and is associated with inflammation | Obesity (Silver Spring).2023 Jan;31(1):171-183. | Human | Cell culture supernatants |
2 | NOD1 modulates decidual stromal cell function to maintain pregnancy in the early trimester | Cell Biochem Funct. 2019 Oct;37(7):464-473 | Human | Cell culture supernatants |
VAL137 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | DNA of neutrophil extracellular traps promote NF-κB-dependent autoimmunity via cGAS/TLR9 in chronic obstructive pulmonary disease | Signal Transduct Target Ther. 2024 Jun 17;9(1):163 | Human | Cell culture supernatant |
2 | Hypermethylation of the glutathione peroxidase 4 gene promoter is associated with the occurrence of immune tolerance phase in chronic hepatitis B | Virol J. 2024 Mar 21;21(1):72 | Human | serum | |
3 | Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis. | Cell Rep. 2023 Aug 29;42(8):112944 | Human | Cell culture supernatants |
VAL145 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | KLF7 promotes colon adenocarcinoma progression through the PDGFB signaling pathway | Int J Biol Sci. 2024 Jan 1;20(1):387-402 | Human | Cell culture supernatant |
VAL146 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | MiR-155-5p improves the insulin sensitivity of trophoblasts by targeting CEBPB in gestational diabetes mellitus | Placenta. 2024 Mar 25:148:1-11 | Human | plasma | |
VAL601 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | Melatonin Induces Analgesic Effects through MT2 Receptor-Mediated Neuroimmune Modulation in the Mice Anterior Cingulate Cortex | Research (Wash DC). 2024 Oct 8:7:0493 | Mouse | cell and tissue homogenates |
2 | Sea buckthorn extract mitigates chronic obstructive pulmonary disease by suppression of ferroptosis via scavenging ROS and blocking p53/MAPK pathways | J Ethnopharmacol. 2025 Jan 10:336:118726. | Mouse | serum | |
3 | Tryptanthrin suppresses multiple inflammasome activation to regulate NASH progression by targeting ASC protein | Phytomedicine. 2024 Aug:131:155758 | Mouse | serum | |
4 | Compact bone mesenchymal stem cells-derived paracrine mediators for cell-free therapy in sepsis | Biochem Biophys Res Commun. 2024 Oct 1:727:150313 | Mouse | cell culture supernatants, tissue homogenates, serum |
5 | Tamarixetin ameliorates cerebral ischemia–reperfusion injury via suppressing nicotinamide adenine dinucleotide phosphate oxidase 2/nucleotide-binding oligomerization domain like receptor family pyrin domain-containing 3 inflammasome activation | Phytother Res. 2024 Aug;38(8):4286-4306. | Mouse | BV-2 cell | |
6 | Unveiling the potent effect of vitamin D: harnessing Nrf2/HO-1 signaling pathways as molecular targets to alleviate urban particulate matter-induced asthma inflammation | BMC Pulm Med. 2024 Jan 25;24(1):55 | Mouse | BALF, serum |
7 | SLC25A3 negatively regulates NLRP3 inflammasome activation by restricting the function of NLRP3 | J Biol Chem. 2024 May;300(5):107233 | Mouse | Cell culture supernatant |
8 | Dimethyl fumarate covalently modifies Cys673 of NLRP3 to exert anti-inflammatory effects. | iScience. 2024 Mar 20;27(4):109544. | Mouse | Cell culture supernatant, tissue homogenates |
9 | Macrophage ferroportin serves as a therapeutic target against bacteria-induced acute lung injury by promoting barrier restoration | iScience. 2022 Dec 1;25(12):105698 | Mouse | BALF | |
10 | Scutellarein alleviates chronic obstructive pulmonary disease through inhibition of ferroptosis by chelating iron and interacting with arachidonate 15-lipoxygenase | Phytother Res. 2023 Oct;37(10):4587-4606. | Mouse | serum | |
11 | A natural chalcone cardamonin inhibits necroptosis and ameliorates dextran sulfate sodium (DSS)-induced colitis by targeting RIPK1/3 kinases | Eur J Pharmacol.2023 Sep 5:954:175840. | Mouse | serum | |
12 | A new class of potent liver injury protective compounds: Structural elucidation, total synthesis and bioactivity study | Acta Pharm Sin B.2023 Aug;13(8):3414-3424. | Mouse | plasma | |
13 | Phosphatidylglucose alleviates atherosclerosis by increasing cholesterol alienation to bile acids and cholesterol efflux in ApoE−/− mice | J Sci Food Agric.2023 Aug 30;103(11):5529-5538. | Mouse | serum | |
14 | The nano-windmill exerts superior anti-inflammatory effects via reducing choline uptake to inhibit macrophage activation | Cell Prolif.2023 Oct;56(10):e13470. | Mouse | Cell culture supernatants |
15 | Neutralizing peripheral circulating IL1β slows the progression of ALS in a lentivirus-infected OPTNE478G mouse model | Animal Model Exp Med.2023 Feb;6(1):18-25. | Mouse | Tissue homogenates |
16 | Enhanced activity of NLRP3 inflammasome and its proinflammatory effect in influenza A viral pneumonia | Mouse | serum, cell culture supernatants |
17 | Ozanimod-Dependent Activation of SIRT3/NF-κB/AIM2 Pathway Attenuates Secondary Injury After Intracerebral Hemorrhage | Mol Neurobiol. 2023 Mar;60(3):1117-1131. | Mouse | Cell culture supernatants |
18 | S100A8-Mediated NLRP3 Inflammasome-Dependent Pyroptosis in Macrophages Facilitates Liver Fibrosis Progression | Cells.2022 Nov 12;11(22):3579. | Mouse | serum | |
19 | Epoxymicheliolide prevents dextran sulfate sodium-induced colitis in mice by inhibiting TAK1-NF-κB pathway and activating Keap1-NRF2 signaling in macrophages | Int Immunopharmacol.2022 Dec;113(Pt A):109404. | Mouse | serum | |
20 | Translational selenium nanotherapeutics counter-acts multiple risk factors to improve surgery-induced cognitive impairment | Chemical Engineering Journal.Volume 441, 1 August 2022, 135984 | Mouse | serum | |
21 | Taurine Alleviates Trimethylamine N-Oxide-Induced Atherosclerosis by Regulating Bile Acid Metabolism in ApoE-/- Mice | J Agric Food Chem. 2022 May 11;70(18):5738-5747 | Mouse | serum | |
22 | High glutamate concentration reverses the inhibitory effect of microglial adenosine 2A receptor on NLRP3 inflammasome assembly and activation | Neurosci Lett. 2022 Jan 19;769:136431 | Mouse | Cell culture supernatants |
23 | FGL2-MCOLN3-Autophagy Axis-Triggered Neutrophil Extracellular Traps Exacerbate Liver Injury in Fulminant Viral Hepatitis | Cell Mol Gastroenterol Hepatol. 2022;14(5):1077-1101 | Mouse | serum | |
24 | Eupalinolide B attenuates lipopolysaccharide-induced acute lung injury through inhibition of NF-κB and MAPKs signaling by targeting TAK1 protein | Int Immunopharmacol. 2022 Oct;111:109148 | Mouse | serum | |
25 | Carfilzomib modulates tumor microenvironment to potentiate immune checkpoint therapy for cancer | EMBO Mol Med. 2022 Jan 11;14(1):e14502 | Mouse | Cell culture supernatants |
26 | Brevilin A Ameliorates Acute Lung Injury and Inflammation Through Inhibition of NF-κB Signaling via Targeting IKKα/β | Front Pharmacol. 2022 Jun 14;13:911157 | Mouse | serum | |
27 | Anti-atherosclerotic effects of geraniin through the gut microbiota-dependent trimethylamine N-oxide (TMAO) pathway in mice | Phytomedicine. 2022 Jul;101:154104 | Mouse | plasma | |
28 | Activation of GIPR Exerts Analgesic and Anxiolytic-Like Effects in the Anterior Cingulate Cortex of Mice | Front Endocrinol (Lausanne). 2022 May 30;13:887238 | Mouse | serum | |
29 | Intelligent lesion blood-brain barrier targeting nano-missiles for Alzheimer's disease treatment by anti-neuroinflammation and neuroprotection | Acta Pharm Sin B. 2022 Apr;12(4):1987-1999 | Mouse | serum, brain |
30 | Ablation of GSDMD Attenuates Neurological Deficits and Neuropathological Alterations After Traumatic Brain Injury | Front Cell Neurosci. 2022 May 20;16:915969 | Mouse | Tissue Lysates |
31 | Anti-atopic effect of Viola yedoensis ethanol extract against 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin dysfunction | J Ethnopharmacol. 2021 Nov 15;280:114474 | Mouse | serum | |
32 | SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target | Cell Res. 2021 Aug;31(8):847-860 | Mouse | serum,cell culture supernatantss |
33 | Multiscale Co-reconstruction of Lung Architectures and Inhalable Materials Spatial Distribution | Adv Sci (Weinh). 2021 Feb 8;8(8):2003941 | Mouse | Cell culture supernatants |
34 | Caspase-11-Gasdermin D-Mediated Pyroptosis Is Involved in the Pathogenesis of Atherosclerosis | Front Pharmacol. 2021 Apr 26;12:657486 | Mouse | Cell culture supernatants |
35 | Adiponectin protects obesity-related glomerulopathy by inhibiting ROS/NF-κB/NLRP3 inflammation pathway | BMC Nephrol. 2021 Jun 10;22(1):218 | Mouse | Cell culture supernatants |
36 | Aggravated MRSA pneumonia secondary to influenza A virus infection is derived from decreased expression of IL-1β | J Med Virol. 2020 Jul 22;92(12):3047-3056 | Mouse | cell culture supernatants,serum |
37 | Bacillus subtilis RZ001 improves intestinal integrity and alleviates colitis by inhibiting the Notch signaling pathway and activating ATOH-1 | Pathog Dis. 2020 Mar 1;78(2):ftaa016 | Mouse | serum | |
38 | Natural Potent NAAA Inhibitor Atractylodin Counteracts LPS-Induced Microglial Activation | Front Pharmacol. 2020 Oct 2;11:577319 | Mouse | Cell culture supernatants |
39 | 4-Octyl itaconate inhibits aerobic glycolysis by targeting GAPDH to exert anti-inflammatory effects | Nat Commun. 2019 Nov 8;10(1):5091 | Mouse | Cell culture supernatants |
40 | MicroRNA‑93 inhibits chondrocyte apoptosis and inflammation in osteoarthritis by targeting the TLR4/NF‑κB signaling pathway | Int J Mol Med. 2019 Feb;43(2):779-790 | Mouse | Cell culture supernatants |
41 | PICK1 Deficiency Induces Autophagy Dysfunction via Lysosomal Impairment and Amplifies Sepsis-Induced Acute Lung Injury | Mediators Inflamm. 2018 Oct 3;2018:6757368 | Mouse | BALF | |
42 | microRNA-182-5p alleviates spinal cord injury by inhibiting inflammation and apoptosis through modulating the TLR4/NF-κB pathway | Int J Clin Exp Pathol. 2018 Jun 1;11(6):2948-2958 | Mouse | Cell culture supernatants |
43 | Menin Deficiency Leads to Depressive-like Behaviors in Mice by Modulating Astrocyte-Mediated Neuroinflammation | Neuron. 2018 Nov 7;100(3):551-563.e7 | Mouse | Cell culture supernatants |
44 | Clemastine Alleviates Depressive-Like Behavior Through Reversing the Imbalance of Microglia-Related Pro-inflammatory State in Mouse Hippocampus | Front Cell Neurosci. 2018 Nov 13;12:412 | Mouse | serum | |
45 | ALS-Associated E478G Mutation in Human OPTN (Optineurin) Promotes Inflammation and Induces Neuronal Cell Death | Front Immunol. 2018 Nov 14;9:2647 | Mouse | cell culture supernatants,Tissue |
46 | Poly(dopamine)-modified carbon nanotube multilayered film and its effects on macrophages | Carbon.Volume 113, March 2017, Pages 176-191 | Mouse | Cell culture supernatants |
VAL602 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | Mycobacterium tuberculosis produces d-serine under hypoxia to limit CD8+ T cell-dependent immunity in mice | Nat Microbiol. 2024 Jul;9(7):1856-1872 | Mouse | serum | |
2 | Intranasal Immunization With a c-di-GMP-Adjuvanted Acellular Pertussis Vaccine Provides Superior Immunity Against Bordetella pertussis in a Mouse Model | Front Immunol. 2022 Apr 13;13:878832 | Mouse | Cell culture supernatants |
VAL603 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | Polygonum perfoliatum L. ethanol extract ameliorates 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin inflammation | J Ethnopharmacol.2024 Jan 30;319(Pt 2):117288. | Mouse | serum | |
2 | A programmed surface on polyetheretherketone for sequentially dictating osteoimmunomodulation and bone regeneration to achieve ameliorative osseointegration under osteoporotic conditions | Bioact Mater. 2022 Feb 1;14:364-376 | Mouse | Cell culture supernatants |
VAL604G | | | | |
Number | Title | Journal | Species | Sample Types |
1 | Melatonin Induces Analgesic Effects through MT2 Receptor-Mediated Neuroimmune Modulation in the Mice Anterior Cingulate Cortex | Research (Wash DC). 2024 Oct 8:7:0493 | Mouse | cell and tissue homogenates |
2 | Composition Characterization of Crossostephium chinense Leaf Essential Oil and Its Anti-Inflammatory Activity Mechanisms | Plants (Basel). 2024 Sep 6;13(17):2506 | Mouse | Cell culture supernatants |
3 | Cannabidiol alleviates carbon tetrachloride-induced liver fibrosis in mice by regulating NF-κB and PPAR-α pathways. | Exp Biol Med (Maywood). 2024 Apr 22:249:10141 | Mouse | serum | |
4 | Polygonum perfoliatum L. ethanol extract ameliorates 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin inflammation | J Ethnopharmacol.2024 Jan 30;319(Pt 2):117288. | Mouse | serum | |
5 | Unveiling the potent effect of vitamin D: harnessing Nrf2/HO-1 signaling pathways as molecular targets to alleviate urban particulate matter-induced asthma inflammation | BMC Pulm Med. 2024 Jan 25;24(1):55 | Mouse | BALF, serum |
6 | Nanomedicine-based co-delivery of a calcium channel inhibitor and a small molecule targeting CD47 for lung cancer immunotherapy | Nat Commun.2023 Nov 11;14(1):7306. | Mouse | Cell culture supernatants |
7 | A natural sesquiterpene lactone isolinderalactone attenuates lipopolysaccharide-induced inflammatory response and acute lung injury through inhibition of NF-κB pathway and activation Nrf2 pathway in macrophages | Int Immunopharmacol.2023 Nov;124(Pt B):110965. | Mouse | serum | |
8 | Scutellarein alleviates chronic obstructive pulmonary disease through inhibition of ferroptosis by chelating iron and interacting with arachidonate 15-lipoxygenase | Phytother Res. 2023 Oct;37(10):4587-4606. | Mouse | serum | |
9 | Autologous olfactory mucosa mesenchymal stem cells treatment improves the neural network in chronic refractory epilepsy | Stem Cell Res Ther.2023 Sep 7;14(1):237. | Mouse | serum | |
10 | A natural chalcone cardamonin inhibits necroptosis and ameliorates dextran sulfate sodium (DSS)-induced colitis by targeting RIPK1/3 kinases | Eur J Pharmacol.2023 Sep 5:954:175840. | Mouse | serum | |
11 | Phosphatidylglucose alleviates atherosclerosis by increasing cholesterol alienation to bile acids and cholesterol efflux in ApoE−/− mice | J Sci Food Agric.2023 Aug 30;103(11):5529-5538. | Mouse | serum | |
12 | Parthenolide targets NLRP3 to treat inflammasome-related diseases | Int Immunopharmacol.2023 Jun:119:110229. | Mouse | serum, cell culture supernatants |
13 | Antibody Assay and Anti-Inflammatory Function Evaluation of Therapeutic Potential of Different Intravenous Immunoglobulins for Alzheimer’s Disease | Int J Mol Sci.2023 Mar 14;24(6):5549. | Mouse | serum | |
14 | MicroRNA-378 inhibits hepatocyte apoptosis during acute liver failure by targeting caspase-9 in mice | Gastroenterol Hepatol. 2023 Feb;46(2):124-134 | Mouse | Serum | |
15 | Epoxymicheliolide prevents dextran sulfate sodium-induced colitis in mice by inhibiting TAK1-NF-κB pathway and activating Keap1-NRF2 signaling in macrophages | Int Immunopharmacol.2022 Dec;113(Pt A):109404. | Mouse | serum | |
16 | Eupalinolide B attenuates lipopolysaccharide-induced acute lung injury through inhibition of NF-κB and MAPKs signaling by targeting TAK1 protein | Int Immunopharmacol. 2022 Oct;111:109148 | Mouse | serum | |
17 | FGL2-MCOLN3-Autophagy Axis-Triggered Neutrophil Extracellular Traps Exacerbate Liver Injury in Fulminant Viral Hepatitis | Cell Mol Gastroenterol Hepatol. 2022;14(5):1077-1101 | Mouse | serum | |
18 | Fragments of bombinakinin M exist in lipopolysaccharide-stimulated skin secretions of Bombina maxima and show lipopolysaccharide-neutralizing activity | J Immunol Methods. 2022 Oct:509:113343 | Mouse | Cell culture supernatant |
19 | Anti-atherosclerotic effects of geraniin through the gut microbiota-dependent trimethylamine N-oxide (TMAO) pathway in mice | Phytomedicine. 2022 Jul;101:154104 | Mouse | plasma | |
20 | Anti-Inflammatory Effect of Acetone Extracts from Microalgae Chlorella sp. WZ13 on RAW264.7 Cells and TPA-induced Ear Edema in Mice | Front. Mar. Sci., 05 July 2022 | Mouse | cells supernatant |
21 | Brevilin A Ameliorates Acute Lung Injury and Inflammation Through Inhibition of NF-κB Signaling via Targeting IKKα/β | Front Pharmacol. 2022 Jun 14;13:911157 | Mouse | serum | |
22 | Taurine Alleviates Trimethylamine N-Oxide-Induced Atherosclerosis by Regulating Bile Acid Metabolism in ApoE-/- Mice | J Agric Food Chem. 2022 May 11;70(18):5738-5747 | Mouse | serum | |
23 | Activation of GIPR Exerts Analgesic and Anxiolytic-Like Effects in the Anterior Cingulate Cortex of Mice | Front Endocrinol (Lausanne). 2022 May 30;13:887238 | Mouse | serum | |
24 | Intranasal Immunization With a c-di-GMP-Adjuvanted Acellular Pertussis Vaccine Provides Superior Immunity Against Bordetella pertussis in a Mouse Model | Front Immunol. 2022 Apr 13;13:878832 | Mouse | Cell culture supernatants |
25 | 4-octyl Itaconate inhibits lipopolysaccharide (LPS)-induced osteoarthritis via activating Nrf2 signaling pathway | J Cell Mol Med. 2022 Mar;26(5):1515-1529 | Mouse | Cell culture supernatants |
26 | Natural exosome-like nanovesicles from edible tea flowers suppress metastatic breast cancer via ROS generation and microbiota modulation | Acta Pharm Sin B. 2022 Feb;12(2):907-923 | Mouse | plasma | |
27 | Carfilzomib modulates tumor microenvironment to potentiate immune checkpoint therapy for cancer | EMBO Mol Med. 2022 Jan 11;14(1):e14502 | Mouse | Cell culture supernatants |
28 | The protective effect of cannabinoid type II receptor agonist AM1241 on ConA-induced liver injury in mice via mitogen-activated protein kinase signaling pathway | Int J Immunopathol Pharmacol. 2021 Jan Dec;35:20587384211035251 | Mouse | Tissue Homogenates |
29 | A two-adjuvant multiantigen candidate vaccine induces superior protective immune responses against SARS-CoV-2 challenge | Cell Rep. 2021 Dec 14;37(11):110112 | Mouse | Cell culture supernatants |
30 | Anti-atopic effect of Viola yedoensis ethanol extract against 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin dysfunction | J Ethnopharmacol. 2021 Nov 15;280:114474 | Mouse | serum | |
31 | SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target | Cell Res. 2021 Aug;31(8):847-860 | Mouse | serum,cell culture supernatantss |
32 | Shufeng Jiedu, a promising herbal therapy for moderate COVID-19: Antiviral and anti-inflammatory properties, pathways of bioactive compounds, and a clinical real-world pragmatic study | Phytomedicine. 2021 May;85:153390 | Mouse | Tissue Homogenates |
33 | Multiscale Co-reconstruction of Lung Architectures and Inhalable Materials Spatial Distribution | Adv Sci (Weinh). 2021 Feb 8;8(8):2003941 | Mouse | Cell culture supernatants |
34 | Dehydrocorydaline Accounts the Majority of Anti-Inflammatory Property of Corydalis Rhizoma in Cultured Macrophage | Evid Based Complement Alternat Med. 2020 Nov 17;2020:4181696 | Mouse | Cell culture supernatants |
35 | Natural Potent NAAA Inhibitor Atractylodin Counteracts LPS-Induced Microglial Activation | Front Pharmacol. 2020 Oct 2;11:577319 | Mouse | Cell culture supernatants |
36 | Evaluation of His6-Metal Assemblies as a Drug Delivery Vehicle in the Treatment of Anterior Segment Disease Using a Corneal Inflammation Model | ACS Biomater Sci Eng. 2020 Jul 13;6(7):4012-4023 | Mouse | Cell culture supernatants |
37 | Illuminating NAD+ Metabolism in Live Cells and In Vivo Using a Genetically Encoded Fluorescent Sensor | Dev Cell. 2020 Apr 20;53(2):240-252.e7 | Mouse | Cell culture supernatants |
38 | Bacillus subtilis RZ001 improves intestinal integrity and alleviates colitis by inhibiting the Notch signaling pathway and activating ATOH-1 | Pathog Dis. 2020 Mar 1;78(2):ftaa016 | Mouse | serum | |
39 | MicroRNA‑93 inhibits chondrocyte apoptosis and inflammation in osteoarthritis by targeting the TLR4/NF‑κB signaling pathway | Int J Mol Med. 2019 Feb;43(2):779-790 | Mouse | Cell culture supernatants |
40 | Activating Adiponectin Signaling with Exogenous AdipoRon Reduces Myelin Lipid Accumulation and Suppresses Macrophage Recruitment after Spinal Cord Injury | J Neurotrauma. 2019 Mar 19;36(6):903-918 | Mouse | Cell culture supernatants |
41 | A thermo-sensitive, injectable and biodegradable in situ hydrogel as a potential formulation for uveitis treatment | J Mater Chem B.Issue 28, 2019 | Mouse | Cell culture supernatants |
42 | miR-155 Aggravates Liver Ischemia/reperfusion Injury by Suppressing SOCS1 in Mice | Transplant Proc. 2018 Dec;50(10):3831-3839 | Mouse | serum, cell culture supernatants |
43 | microRNA-182-5p alleviates spinal cord injury by inhibiting inflammation and apoptosis through modulating the TLR4/NF-κB pathway | Int J Clin Exp Pathol. 2018 Jun 1;11(6):2948-2958 | Mouse | Cell culture supernatants |
44 | Anti-inflammatory effect of low molecular weight fucoidan from Saccharina japonica on atherosclerosis in apoE-knockout mice | Int J Biol Macromol. 2018 Oct 15;118(Pt A):365-374 | Mouse | aorta and liver tissues |
45 | Self-Recognition of an Inducible Host lncRNA by RIG-I Feedback Restricts Innate Immune Response | Cell. 2018 May 3;173(4):906-919.e13 | Mouse | serum, cell culture supernatants |
46 | ALS-Associated E478G Mutation in Human OPTN (Optineurin) Promotes Inflammation and Induces Neuronal Cell Death | Front Immunol. 2018 Nov 14;9:2647 | Mouse | cell culture supernatants,Tissue |
47 | Poly(dopamine)-modified carbon nanotube multilayered film and its effects on macrophages | Carbon.Volume 113, March 2017, Pages 176-191 | Mouse | Cell culture supernatants |
48 | Mir-24 regulates hepatocyte apoptosis via BIM during acute liver failure | Am J Transl Res. 2017 Nov 15;9(11):4925-4935 | Mouse | serum | |
49 | MicroRNA-182-5p Ameliorates Liver Ischemia-Reperfusion Injury by Suppressing Toll-Like Receptor 4 | Transplant Proc. 2016 Oct;48(8):2809-2814 | Mouse | serum, cell culture supernatants |
50 | mTORC1-mediated downregulation of COX2 restrains tumor growth caused by TSC2 deficiency | Oncotarget. 2016 May 10;7(19):28435-47 | Mouse | Cell culture supernatants |
51 | miR-146a ameliorates liver ischemia/reperfusion injury by suppressing IRAK1 and TRAF6 | PLoS One. 2014 Jul 2;9(7):e101530 | Mouse | Cell culture supernatants |
52 | Wogonoside displays anti-inflammatory effects through modulating inflammatory mediator expression using RAW264.7 cells | J Ethnopharmacol. 2013 Jun 21;148(1):271-6 | Mouse | Cell culture supernatants |
VAL605 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | Human umbilical mesenchymal stem cell-derived exosomes alleviate bone destruction and regulate bone immunity via the aryl hydrocarbon receptor to treat rheumatoid arthritis | Int Immunopharmacol. 2024 Dec 25;143(Pt 2):113340 | Mouse | serum | |
2 | Fragments of bombinakinin M exist in lipopolysaccharide-stimulated skin secretions of Bombina maxima and show lipopolysaccharide-neutralizing activity | J Immunol Methods. 2022 Oct:509:113343 | Mouse | Cell culture supernatant |
3 | 4-octyl Itaconate inhibits lipopolysaccharide (LPS)-induced osteoarthritis via activating Nrf2 signaling pathway | J Cell Mol Med. 2022 Mar;26(5):1515-1529 | Mouse | Cell culture supernatants |
4 | Shufeng Jiedu, a promising herbal therapy for moderate COVID-19: Antiviral and anti-inflammatory properties, pathways of bioactive compounds, and a clinical real-world pragmatic study | Phytomedicine. 2021 May;85:153390 | Mouse | Tissue Homogenates |
5 | SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target | Cell Res. 2021 Aug;31(8):847-860 | Mouse | serum,cell culture supernatants |
6 | Anti-inflammatory effect of low molecular weight fucoidan from Saccharina japonica on atherosclerosis in apoE-knockout mice | Int J Biol Macromol. 2018 Oct 15;118(Pt A):365-374 | Mouse | aorta and liver tissues |
7 | ALS-Associated E478G Mutation in Human OPTN (Optineurin) Promotes Inflammation and Induces Neuronal Cell Death | Front Immunol. 2018 Nov 14;9:2647 | Mouse | cell culture supernatants,Tissue |
8 | Poly(dopamine)-modified carbon nanotube multilayered film and its effects on macrophages | Carbon.Volume 113, March 2017, Pages 176-191 | Mouse | Cell culture supernatants |
VAL606 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | CLN-617 retains IL-2 and IL-12 in injected tumors to drive robust and systemic immune-mediated antitumor activity | Cancer Immunol Res. 2024 Aug 1;12(8):1022-1038 | Mouse | serum, tissue lysis |
VAL607 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | Melatonin Induces Analgesic Effects through MT2 Receptor-Mediated Neuroimmune Modulation in the Mice Anterior Cingulate Cortex | Research (Wash DC). 2024 Oct 8:7:0493 | Mouse | cell and tissue homogenates |
2 | An armed oncolytic virus enhances the efficacy of tumor-infiltrating lymphocyte therapy by converting tumors to artificial antigen-presenting cells in situ | Mol Ther. 2022 Dec 7;30(12):3658-3676 | Mouse | Cell culture supernatants |
3 | Intranasal Immunization With a c-di-GMP-Adjuvanted Acellular Pertussis Vaccine Provides Superior Immunity Against Bordetella pertussis in a Mouse Model | Front Immunol. 2022 Apr 13;13:878832 | Mouse | Cell culture supernatants |
4 | The protective effect of cannabinoid type II receptor agonist AM1241 on ConA-induced liver injury in mice via mitogen-activated protein kinase signaling pathway | Int J Immunopathol Pharmacol. 2021 Jan-Dec;35:20587384211035251 | Mouse | Tissue Homogenates |
5 | Shufeng Jiedu, a promising herbal therapy for moderate COVID-19: Antiviral and anti-inflammatory properties, pathways of bioactive compounds, and a clinical real-world pragmatic study | Phytomedicine. 2021 May;85:153390 | Mouse | Tissue Homogenates |
6 | SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target | Cell Res. 2021 Aug;31(8):847-860 | Mouse | serum,cell culture supernatants |
7 | Irgm1 knockout indirectly inhibits regeneration after skeletal muscle injury in mice | Int Immunopharmacol. 2020 Jul;84:106515 | Mouse | serum, tissue homogenates |
8 | Evaluation of the protective immunity of a novel subunit fusion vaccine in a murine model of systemic MRSA infection | PLoS One. 2013 Dec 4;8(12):e81212 | Mouse | Cell culture supernatants |
VAL608 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | A gain-of-function mutation in Tnni2 impeded bone development through increasing Hif3a expression in DA2B mice | PLoS Genet. 2014 Oct 23;10(10):e1004589 | Mouse | Cell culture supernatants |
VAL609 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | Composition Characterization of Crossostephium chinense Leaf Essential Oil and Its Anti-Inflammatory Activity Mechanisms | Plants (Basel). 2024 Sep 6;13(17):2506 | Mouse | Cell culture supernatants |
2 | Melatonin Induces Analgesic Effects through MT2 Receptor-Mediated Neuroimmune Modulation in the Mice Anterior Cingulate Cortex | Research (Wash DC). 2024 Oct 8:7:0493 | Mouse | cell and tissue homogenates |
3 | The zinc transporter Slc30a1 (ZnT1) in macrophages plays a protective role against attenuated Salmonella | Elife. 2024 Oct 30:13:e89509 | Mouse | serum | |
4 | Cannabidiol alleviates carbon tetrachloride-induced liver fibrosis in mice by regulating NF-κB and PPAR-α pathways. | Exp Biol Med (Maywood). 2024 Apr 22:249:10141 | Mouse | serum | |
5 | MicroRNA-378 inhibits hepatocyte apoptosis during acute liver failure by targeting caspase-9 in mice | Gastroenterol Hepatol. 2023 Feb;46(2):124-134 | Mouse | Serum | |
6 | Macrophage ferroportin serves as a therapeutic target against bacteria-induced acute lung injury by promoting barrier restoration | iScience. 2022 Dec 1;25(12):105698 | Mouse | BALF | |
7 | Open-Ring Butenolides from a Marine-Derived Anti-Neuroinflammatory Fungus Aspergillus terreus Y10 | Mar Drugs. 2018 Nov 2;16(11):428 | Mouse | Cell culture supernatant |
8 | Fragments of bombinakinin M exist in lipopolysaccharide-stimulated skin secretions of Bombina maxima and show lipopolysaccharide-neutralizing activity | J Immunol Methods. 2022 Oct:509:113343 | Mouse | Cell culture supernatant |
9 | Anti-Inflammatory Effect of Acetone Extracts from Microalgae Chlorella sp. WZ13 on RAW264.7 Cells and TPA-induced Ear Edema in Mice | Front. Mar. Sci., 05 July 2022 | Mouse | cells supernatant |
10 | Programmed surface on poly(aryl-ether-ether-ketone) initiating immune mediation and fulfilling bone regeneration sequentially | Innovation (Camb). 2021 Aug 5;2(3):100148 | Mouse | Cell culture supernatant |
11 | Parthenolide targets NLRP3 to treat inflammasome-related diseases | Int Immunopharmacol.2023 Jun:119:110229. | Mouse | serum, cell culture supernatants |
12 | Phosphatidylglucose alleviates atherosclerosis by increasing cholesterol alienation to bile acids and cholesterol efflux in ApoE−/− mice | J Sci Food Agric.2023 Aug 30;103(11):5529-5538. | Mouse | serum | |
13 | Antibody Assay and Anti-Inflammatory Function Evaluation of Therapeutic Potential of Different Intravenous Immunoglobulins for Alzheimer’s Disease | Int J Mol Sci.2023 Mar 14;24(6):5549. | Mouse | serum | |
14 | Combined Application of Exosomes and FPR2 Agonist LXA4 in Controlling Fetal Membrane Inflammation and Promoting Fetal Membrane Tissue Repair | Reprod Sci.2023 Jun;30(6):1979-1993. | Mouse | plasma | |
15 | Epoxymicheliolide prevents dextran sulfate sodium-induced colitis in mice by inhibiting TAK1-NF-κB pathway and activating Keap1-NRF2 signaling in macrophages | Int Immunopharmacol.2022 Dec;113(Pt A):109404. | Mouse | serum | |
16 | Mesenchymal stem cell-derived extracellular vesicles attenuate tPA-induced blood–brain barrier disruption in murine ischemic stroke models | Acta Biomater. 2022 Dec:154:424-442. | Mouse | Cell culture supernatants |
17 | Combined delivery of small molecule and protein drugs as synergistic therapeutics for treating corneal neovascularization by a one-pot coassembly strategy | Mater Today Bio.2022 Oct 8:17:100456. | Mouse | Cell culture supernatants |
18 | Taurine Alleviates Trimethylamine N-Oxide-Induced Atherosclerosis by Regulating Bile Acid Metabolism in ApoE-/- Mice | J Agric Food Chem. 2022 May 11;70(18):5738-5747 | Mouse | serum | |
19 | Natural exosome-like nanovesicles from edible tea flowers suppress metastatic breast cancer via ROS generation and microbiota modulation | Acta Pharm Sin B. 2022 Feb;12(2):907-923 | Mouse | plasma | |
20 | Intranasal Immunization With a c-di-GMP-Adjuvanted Acellular Pertussis Vaccine Provides Superior Immunity Against Bordetella pertussis in a Mouse Model | Front Immunol. 2022 Apr 13;13:878832 | Mouse | Cell culture supernatants |
21 | FGL2-MCOLN3-Autophagy Axis-Triggered Neutrophil Extracellular Traps Exacerbate Liver Injury in Fulminant Viral Hepatitis | Cell Mol Gastroenterol Hepatol. 2022;14(5):1077-1101 | Mouse | serum | |
22 | Eupalinolide B attenuates lipopolysaccharide-induced acute lung injury through inhibition of NF-κB and MAPKs signaling by targeting TAK1 protein | Int Immunopharmacol. 2022 Oct;111:109148 | Mouse | serum | |
23 | Discovery of Pyrazolo[3,4-d]pyridazinone Derivatives as Selective DDR1 Inhibitors via Deep Learning Based Design, Synthesis, and Biological Evaluation | J. Med. Chem. 2022, 65, 1, 103–119 | Mouse | serum | |
24 | Carfilzomib modulates tumor microenvironment to potentiate immune checkpoint therapy for cancer | EMBO Mol Med. 2022 Jan 11;14(1):e14502 | Mouse | Cell culture supernatants |
25 | Brevilin A Ameliorates Acute Lung Injury and Inflammation Through Inhibition of NF-κB Signaling via Targeting IKKα/β | Front Pharmacol. 2022 Jun 14;13:911157 | Mouse | serum | |
26 | Anti-atherosclerotic effects of geraniin through the gut microbiota-dependent trimethylamine N-oxide (TMAO) pathway in mice | Phytomedicine. 2022 Jul;101:154104 | Mouse | plasma | |
27 | Activation of GIPR Exerts Analgesic and Anxiolytic-Like Effects in the Anterior Cingulate Cortex of Mice | Front Endocrinol (Lausanne). 2022 May 30;13:887238 | Mouse | serum | |
28 | Ablation of GSDMD Attenuates Neurological Deficits and Neuropathological Alterations After Traumatic Brain Injury | Front Cell Neurosci. 2022 May 20;16:915969 | Mouse | Tissue Lysates |
29 | 4-octyl Itaconate inhibits lipopolysaccharide (LPS)-induced osteoarthritis via activating Nrf2 signaling pathway | J Cell Mol Med. 2022 Mar;26(5):1515-1529 | Mouse | Cell culture supernatants |
30 | The protective effect of cannabinoid type II receptor agonist AM1241 on ConA-induced liver injury in mice via mitogen-activated protein kinase signaling pathway | Int J Immunopathol Pharmacol. 2021 Jan-Dec;35:20587384211035251 | Mouse | Tissue Homogenates |
31 | Shufeng Jiedu, a promising herbal therapy for moderate COVID-19: Antiviral and anti-inflammatory properties, pathways of bioactive compounds, and a clinical real-world pragmatic study | Phytomedicine. 2021 May;85:153390 | Mouse | Tissue Homogenates |
32 | SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target | Cell Res. 2021 Aug;31(8):847-860 | Mouse | serum,cell culture supernatants |
33 | Multiscale Co-reconstruction of Lung Architectures and Inhalable Materials Spatial Distribution | Adv Sci (Weinh). 2021 Feb 8;8(8):2003941 | Mouse | Cell culture supernatants |
34 | Anti-atopic effect of Viola yedoensis ethanol extract against 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin dysfunction | J Ethnopharmacol. 2021 Nov 15;280:114474 | Mouse | serum | |
35 | A two-adjuvant multiantigen candidate vaccine induces superior protective immune responses against SARS-CoV-2 challenge | Cell Rep. 2021 Dec 14;37(11):110112 | Mouse | Cell culture supernatants |
36 | A more defective substrate leads to a less defective passive layer: Enhancing the mechanical strength, corrosion resistance and anti-inflammatory response of the low-modulus Ti-45Nb alloy by grain refinement | Acta Biomater. 2021 May;126:524-536 | Mouse | Cell culture supernatants |
37 | Paroxetine suppresses reactive microglia-mediated but not lipopolysaccharide-induced inflammatory responses in primary astrocytes | J Neuroinflammation. 2020 Feb 5;17(1):50 | Mouse | Cell culture medium |
38 | Natural Potent NAAA Inhibitor Atractylodin Counteracts LPS-Induced Microglial Activation | Front Pharmacol. 2020 Oct 2;11:577319 | Mouse | Cell culture supernatants |
39 | Evaluation of His6-Metal Assemblies as a Drug Delivery Vehicle in the Treatment of Anterior Segment Disease Using a Corneal Inflammation Model | ACS Biomater Sci Eng. 2020 Jul 13;6(7):4012-4023 | Mouse | Cell culture supernatants |
40 | Bacillus subtilis RZ001 improves intestinal integrity and alleviates colitis by inhibiting the Notch signaling pathway and activating ATOH-1 | Pathog Dis. 2020 Mar 1;78(2):ftaa016 | Mouse | serum | |
41 | Activating Adiponectin Signaling with Exogenous AdipoRon Reduces Myelin Lipid Accumulation and Suppresses Macrophage Recruitment after Spinal Cord Injury | J Neurotrauma. 2019 Mar 19;36(6):903-918 | Mouse | Cell culture supernatants |
42 | MicroRNA‑93 inhibits chondrocyte apoptosis and inflammation in osteoarthritis by targeting the TLR4/NF‑κB signaling pathway | Int J Mol Med. 2019 Feb;43(2):779-790 | Mouse | Cell culture supernatants |
43 | ALS-Associated E478G Mutation in Human OPTN (Optineurin) Promotes Inflammation and Induces Neuronal Cell Death | Front Immunol. 2018 Nov 14;9:2647 | Mouse | cell culture supernatants,Tissue |
44 | Resolvin D1 attenuates imiquimod-induced psoriasiform dermatitis in mice through MAPKs and NF-κB pathways | J Dermatol Sci. 2018 Feb;89(2):127-135 | Mouse | serum | |
45 | miR-155 Aggravates Liver Ischemia/reperfusion Injury by Suppressing SOCS1 in Mice | Transplant Proc. 2018 Dec;50(10):3831-3839 | Mouse | serum, cell culture supernatants |
46 | PICK1 Deficiency Induces Autophagy Dysfunction via Lysosomal Impairment and Amplifies Sepsis-Induced Acute Lung Injury | Mediators Inflamm. 2018 Oct 3;2018:6757368 | Mouse | BALF | |
47 | microRNA-182-5p alleviates spinal cord injury by inhibiting inflammation and apoptosis through modulating the TLR4/NF-κB pathway | Int J Clin Exp Pathol. 2018 Jun 1;11(6):2948-2958 | Mouse | Cell culture supernatants |
48 | Poly(dopamine)-modified carbon nanotube multilayered film and its effects on macrophages | Carbon.Volume 113, March 2017, Pages 176-191 | Mouse | Cell culture supernatants |
49 | Mir-24 regulates hepatocyte apoptosis via BIM during acute liver failure | Am J Transl Res. 2017 Nov 15;9(11):4925-4935 | Mouse | serum | |
50 | MicroRNA-182-5p Ameliorates Liver Ischemia-Reperfusion Injury by Suppressing Toll-Like Receptor 4 | Transplant Proc. 2016 Oct;48(8):2809-2814 | Mouse | serum, cell culture supernatants |
51 | CD11b deficiency suppresses intestinal tumor growth by reducing myeloid cell recruitment | Sci Rep. 2015 Nov 3;5:15948 | Mouse | Serum | |
52 | miR-146a ameliorates liver ischemia/reperfusion injury by suppressing IRAK1 and TRAF6 | PLoS One. 2014 Jul 2;9(7):e101530 | Mouse | Cell culture supernatants |
53 | Wogonoside displays anti-inflammatory effects through modulating inflammatory mediator expression using RAW264.7 cells | J Ethnopharmacol. 2013 Jun 21;148(1):271-6 | Mouse | Cell culture supernatants |
VAL610 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | Composition Characterization of Crossostephium chinense Leaf Essential Oil and Its Anti-Inflammatory Activity Mechanisms | Plants (Basel). 2024 Sep 6;13(17):2506 | Mouse | Cell culture supernatants |
2 | Evaluation of the protective immunity of a novel subunit fusion vaccine in a murine model of systemic MRSA infection | PLoS One. 2013 Dec 4;8(12):e81212 | Mouse | Cell culture supernatants |
VAL611 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | Human umbilical mesenchymal stem cell-derived exosomes alleviate bone destruction and regulate bone immunity via the aryl hydrocarbon receptor to treat rheumatoid arthritis | Int Immunopharmacol. 2024 Dec 25;143(Pt 2):113340 | Mouse | serum | |
2 | Programmed surface on poly(aryl-ether-ether-ketone) initiating immune mediation and fulfilling bone regeneration sequentially | Innovation (Camb). 2021 Aug 5;2(3):100148 | Mouse | Cell culture supernatant |
3 | Bidirectional regulation between tumor cell-intrinsic PD-L1 and TGF-β1 in epithelial-to-mesenchymal transition in melanoma | Transl Cancer Res. 2022 Oct;11(10):3698-3710. | Mouse | Cell culture supernatants;Tissue Homogenates |
4 | Targeting HIC1/TGF-β axis-shaped prostate cancer microenvironment restrains its progression | Cell Death Dis. 2022 Jul 19;13(7):624. | Mouse | serum | |
5 | Immune dysfunction induced by 2,6-dichloro-1,4-benzoquinone, an emerging water disinfection byproduct, due to the defects of host-microbiome interactions | Chemosphere. 2022 May;294:133777 | Mouse | serum | |
6 | Ablation of GSDMD Attenuates Neurological Deficits and Neuropathological Alterations After Traumatic Brain Injury | Front Cell Neurosci. 2022 May 20;16:915969 | Mouse | Tissue Lysates |
7 | Targeted exosomes for co-delivery of siFGL1 and siTGF-β1 trigger combined cancer immunotherapy by remodeling immunosuppressive tumor microenvironment | Chemical Engineering Journal.Volume 421, Part 1, 1 October 2021, 129774 | Mouse | Cell culture supernatants |
8 | A more defective substrate leads to a less defective passive layer: Enhancing the mechanical strength, corrosion resistance and anti-inflammatory response of the low-modulus Ti-45Nb alloy by grain refinement | Acta Biomater. 2021 May;126:524-536 | Mouse | Cell culture supernatants |
VAL612 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | Npc1 deficiency impairs microglia function via TREM2-mTOR signaling in Niemann-Pick disease type C | Biochim Biophys Acta Mol Basis Dis. 2024 Dec;1870(8):167478 | Mouse | Serum | |
2 | TIPE1 limits virus replication by disrupting PKM2/ HIF-1α/ glycolysis feedback loop | Free Radic Biol Med. 2024 Aug 20:221:52-63 | Mouse | Cell culture supernatants, serum |
3 | Tim-4 reprograms cholesterol metabolism to suppress antiviral innate immunity by disturbing the Insig1-SCAP interaction in macrophages | Cell Rep. 2022 Nov 29;41(9):111738 | Mouse | Tissue Homogenates,Cell culture supernatants,Serum |
4 | A two-adjuvant multiantigen candidate vaccine induces superior protective immune responses against SARS-CoV-2 challenge | Cell Rep. 2021 Dec 14;37(11):110112 | Mouse | Cell culture supernatants |
VAL619 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | Sea buckthorn extract mitigates chronic obstructive pulmonary disease by suppression of ferroptosis via scavenging ROS and blocking p53/MAPK pathways | J Ethnopharmacol. 2025 Jan 10:336:118726. | Mouse | serum | |
2 | Activating Adiponectin Signaling with Exogenous AdipoRon Reduces Myelin Lipid Accumulation and Suppresses Macrophage Recruitment after Spinal Cord Injury | J Neurotrauma. 2019 Mar 19;36(6):903-918 | Mouse | Cell culture supernatants |
VAL626 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | Evaluation of the protective immunity of a novel subunit fusion vaccine in a murine model of systemic MRSA infection | PLoS One. 2013 Dec 4;8(12):e81212 | Mouse | Cell culture supernatants |
VAL901 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | mTORC1-mediated downregulation of COX2 restrains tumor growth caused by TSC2 deficiency | Oncotarget. 2016 May 10;7(19):28435-47 | Mouse | Cell culture supernatants |
2 | Triptolide attenuates acute small-for-size liver graft injury in rats by inhibition of Toll-like receptor 4 | Transplant Proc. 2014 Dec;46(10):3303-8 | Rat | serum | |
VAL902 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | Low bone turnover is associated with advanced glycation end-products, oxidative stress, and inflammation induced by type 2 diabetes mellitus | FASEB J. 2024 Aug 15;38(15):e23871 | Rat | serum, cell supernatant |
2 | Probiotic strains improve high-fat diet-induced hypercholesterolemia through modulating gut microbiota in ways different from atorvastatin | Food Funct. 2019 Sep 18;10(9):6098-6109 | Rat | Serum | |
3 | Triptolide attenuates acute small-for-size liver graft injury in rats by inhibition of Toll-like receptor 4 | Transplant Proc. 2014 Dec;46(10):3303-8 | Rat | serum | |
VAL903 | | | | | |
Number | Title | Journal | Species | Sample Types |
1 | Probiotic strains improve high-fat diet-induced hypercholesterolemia through modulating gut microbiota in ways different from atorvastatin | Food Funct. 2019 Sep 18;10(9):6098-6109 | Rat | Serum | |