Tocriscreen Kinase Inhibitor Library
Tocris Bioscience a Bio-Techne Brand
Key Product Details
Description: | A bioactive compound library of 160 kinase inhibitors (250 μL 10 mM DMSO solutions) for high-throughput screening, high-content screening and chemical biology applications |
Key Format Details: |
![]() The Tocriscreen Kinase Inhibitors Library contains bioactive compounds covering a diverse range of kinases, including established enzymes and more novel targets. |
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Citations for Tocriscreen Kinase Inhibitor Library (19)
Citations are publications that use Bio-Techne products. Selected citations for Tocriscreen Kinase Inhibitor Library include:
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Gull et al.
(2022)
Screening of chemical libraries using xenopus embryos and tadpoles for phenotypic drug discovery.
Cold Spring Harb.Protoc..
2022;
PMID: 36180216 -
Carlson et al.
(2022)
Discovery and characterization of multiple classes of human CatSper blockers.
Chem Med Chem.
17:e202000499
PMID: 35644882 -
Lee et al.
(2021)
A screen of kinase inhibitors reveals a potential role of Chk1 in regulating Hydra head regeneration and maintenance.
Int J Dev Biol.
65:523
PMID: 3454979 -
Hewage et al.
(2020)
Chemical manipulation of abscisic acid signaling: a new approach to abiotic and biotic stress management in agriculture.
Adv.Sci..
7:2001265
PMID: 32999840 -
Sherman and Rossi
(2019)
A Novel Three-Dimensional Glioma Blood-Brain Barrier Model for High-Throughput Testing of Tumoricidal Capability.
Front Oncol.
9:351
PMID: 31131260 -
Chaudhari et al.
(2019)
Transient c-Src Suppression During Endodermal Commitment of Human Induced Pluripotent Stem Cells Results in Abnormal Profibrotic Cholangiocyte-Like Cells.
Stem Cells.
37:306
PMID: 30471152 -
Yang et al.
(2019)
NTRK1 is a positive regulator of YAP oncogenic function.
Oncogene.
38:2778
PMID: 30542115 -
Moret et al.
(2019)
Cheminformatics tools for analyzing and designing optimized small-molecule collections and libraries.
Cell Chem Biol.
26:765
PMID: 30956147 -
Wang et al.
(2019)
EGFR-Aurka signaling rescues polarity and regeneration defects in dystrophin-deficient muscle stem cells by increasing asymmetric divisions.
Cell Stem Cell.
24:419
PMID: 30713094 -
Markussen et al.
(2018)
GSK3 is a negative regulator of the thermogenic program in brown adipocytes.
Sci.Rep..
8:3469
PMID: 29472592 -
Moeschler et al.
(2018)
1-Benzyl-3-cetyl-2-methylimidazolium Iodide (NH125) Is a Broad-Spectrum Inhibitor of Virus Entry with Lysosomotropic Features.
Viruses.
10:E306
PMID: 29874821 -
Azad et al.
(2018)
A LATS biosensor screen identifies VEGFR as a regulator of the Hippo pathway in angiogenesis.
Nat Commun.
9:1061
PMID: 29535383 -
Tomilov et al.
(2018)
Idebenone is a cytoprotective insulin sensitizer whose mechanism is Shc inhibition.
Pharmacol Res.
137:89
PMID: 30290222 -
Jacoby et al.
(2017)
Protocols for the design of kinase-focused compound libraries.
Mol Inform.
37:e1700119
PMID: 29116686 -
Sandilands et al.
(2015)
p70S6K is regulated by focal adhesion kinase and is required for Src-selective autophagy.
Cell Signal..
27:1816
PMID: 26071201 -
Tandon et al.
(2015)
SD-208, a novel protein kinase D inhibitor, blocks prostate cancer cell proliferation and tumor growth in vivo by inducing G2/M cell cycle arrest.
PLoS One.
10:e0119346
PMID: 25747583 -
FitzGerald et al.
(2014)
A high through-put screen for small molecules modulating MCM2 phosphorylation identifies Ryuvidine as an inducer of the DNA damage response.
PLoS One.
9:e98891
PMID: 24902048 -
Acevedo et al.
(2014)
Phosphorylation of amyloid precursor protein at threonine 668 is essential for its copper-responsive trafficking in SH-SY5Y neuroblastoma cells.
J Biol Chem.
289:11007
PMID: 24610780 -
Moujalled et al.
(2013)
Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress.
PLoS One.
8:e67433
PMID: 23840699
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