Tocriscreen Kinase Inhibitor Library

Name: Tocriscreen Kinase Inhibitor Library
Brand: Tocris Bioscience
SKU: 6268

Tocris Bioscience a Bio-Techne Brand

Catalog # 6268

Citations (19)

COA / SDS

New Version Available - 7844

Discontinued Product

6268 has been discontinued and is replaced by 7844.

Key Product Details

Description:

A bioactive compound library of 160 kinase inhibitors (250 μL 10 mM DMSO solutions) for high-throughput screening, high-content screening and chemical biology applications

Key Format Details:

96-well racks with Matrix storage tubes & SepraSeal caps
Pre-dissolved in DMSO
Compounds arranged 80 per rack with two racks per library

Many compounds are exclusive to Tocris
Full chemical and biological data available
Exceptional purity

Target Classes Covered by the Tocriscreen Kinases Inhibitors Library

The Tocriscreen Kinase Inhibitors Library contains bioactive compounds covering a diverse range of kinases, including established enzymes and more novel targets.

View Full Technical Details for Tocriscreen Kinase Inhibitor Library

Product Description for Tocriscreen Kinase Inhibitor Library

Tocriscreen Kinase Inhibitor Library is a collection of 160 kinase inhibitors supplied pre-dissolved in DMSO (250 μL 10 mM solution). The Tocriscreen Kinase Inhibitor Library contains compounds targeting >60 different kinases, including extensive coverage of well-established targets such as VEFGR, AKT and TGFβR as well as more novel targets such as LIMK, Hapsin, NUAK1 and DYRK.

If this library does not suit your needs, please submit your requirements through our Tocriscreen PRO custom compound library service.

Request Compound List

A list of the compounds available in the Tocriscreen Kinase Inhibitor Library can be requested in Excel or SD format via our Tocriscreen & Custom Library Inquiries form.

Technical Data for Tocriscreen Kinase Inhibitor Library

Storage	Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Citations for Tocriscreen Kinase Inhibitor Library (19)

Showing 1 - 10 of 19 citations Showing All

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Citations are publications that use Bio-Techne products. Selected citations for Tocriscreen Kinase Inhibitor Library include:

Gull et al. (2022) Screening of chemical libraries using xenopus embryos and tadpoles for phenotypic drug discovery. Cold Spring Harb.Protoc.. 2022;
PMID: 36180216
Carlson et al. (2022) Discovery and characterization of multiple classes of human CatSper blockers. Chem Med Chem. 17:e202000499
PMID: 35644882
Lee et al. (2021) A screen of kinase inhibitors reveals a potential role of Chk1 in regulating Hydra head regeneration and maintenance. Int J Dev Biol. 65:523
PMID: 3454979
Hewage et al. (2020) Chemical manipulation of abscisic acid signaling: a new approach to abiotic and biotic stress management in agriculture. Adv.Sci.. 7:2001265
PMID: 32999840
Sherman and Rossi (2019) A Novel Three-Dimensional Glioma Blood-Brain Barrier Model for High-Throughput Testing of Tumoricidal Capability. Front Oncol. 9:351
PMID: 31131260
Chaudhari et al. (2019) Transient c-Src Suppression During Endodermal Commitment of Human Induced Pluripotent Stem Cells Results in Abnormal Profibrotic Cholangiocyte-Like Cells. Stem Cells. 37:306
PMID: 30471152
Yang et al. (2019) NTRK1 is a positive regulator of YAP oncogenic function. Oncogene. 38:2778
PMID: 30542115
Moret et al. (2019) Cheminformatics tools for analyzing and designing optimized small-molecule collections and libraries. Cell Chem Biol. 26:765
PMID: 30956147
Wang et al. (2019) EGFR-Aurka signaling rescues polarity and regeneration defects in dystrophin-deficient muscle stem cells by increasing asymmetric divisions. Cell Stem Cell. 24:419
PMID: 30713094
Markussen et al. (2018) GSK3 is a negative regulator of the thermogenic program in brown adipocytes. Sci.Rep.. 8:3469
PMID: 29472592
Moeschler et al. (2018) 1-Benzyl-3-cetyl-2-methylimidazolium Iodide (NH125) Is a Broad-Spectrum Inhibitor of Virus Entry with Lysosomotropic Features. Viruses. 10:E306
PMID: 29874821
Azad et al. (2018) A LATS biosensor screen identifies VEGFR as a regulator of the Hippo pathway in angiogenesis. Nat Commun. 9:1061
PMID: 29535383
Tomilov et al. (2018) Idebenone is a cytoprotective insulin sensitizer whose mechanism is Shc inhibition. Pharmacol Res. 137:89
PMID: 30290222
Jacoby et al. (2017) Protocols for the design of kinase-focused compound libraries. Mol Inform. 37:e1700119
PMID: 29116686
Sandilands et al. (2015) p70S6K is regulated by focal adhesion kinase and is required for Src-selective autophagy. Cell Signal.. 27:1816
PMID: 26071201
Tandon et al. (2015) SD-208, a novel protein kinase D inhibitor, blocks prostate cancer cell proliferation and tumor growth in vivo by inducing G2/M cell cycle arrest. PLoS One. 10:e0119346
PMID: 25747583
FitzGerald et al. (2014) A high through-put screen for small molecules modulating MCM2 phosphorylation identifies Ryuvidine as an inducer of the DNA damage response. PLoS One. 9:e98891
PMID: 24902048
Acevedo et al. (2014) Phosphorylation of amyloid precursor protein at threonine 668 is essential for its copper-responsive trafficking in SH-SY5Y neuroblastoma cells. J Biol Chem. 289:11007
PMID: 24610780
Moujalled et al. (2013) Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress. PLoS One. 8:e67433
PMID: 23840699

There are no citations that match your criteria.

Showing 1 - 10 of 19 citations Showing All

Product Documents for Tocriscreen Kinase Inhibitor Library

COA

Certificate of Analysis is currently unavailable on-line. Please contact Customer Service.