tBPC

Name: tBPC
Brand: Tocris Bioscience
SKU: 6411

Tocris Bioscience, part of Bio-Techne | Catalog # 6411

COA / SDS

Positive allosteric modulator of NPY Y4 receptor

Discontinued Product

6411 has been discontinued. View all NPY Receptor Agonists products.

Key Product Details

Description:	Positive allosteric modulator of NPY Y₄ receptor
Chemical Name:	2-[4-(1,1-Dimethylethyl)phenoxy]cyclohexanol
Purity:	≥98% (HPLC)
Molecular Weight:	248.36

View Full Technical Details for tBPC

Technical Data
Citations

Biological Activity for tBPC

tBPC is a positive allosteric modulator of neuropeptide Y receptor 4 (Y₄R). Potentiates Y₄R response to pancreatic polypeptide (PP), neuropeptide Y (NPY) and peptide YY (PYY) (EC₅₀ values are 0.03, 0.4 and 0.5 nM respectively). Shows selectivity for Y₄R over Y₁R, Y₂R and Y₅R.

Technical Data for tBPC

M. Wt	248.36
Formula	C₁₆H₂₄O₂
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	1942-71-8
PubChem ID	16033
InChi Key	FTIXUILRMBSXNS-UHFFFAOYSA-N
Smiles	CC(C)(C1=CC=C(C=C1)OC2CCCCC2O)C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for tBPC

References are publications that support the biological activity of the product.

Schubert Identification and characterization of the first selective Y₄ receptor positive allosteric modulator. J.Med.Chem. 2017 PMID: 28795803

tBPC

Tocris Bioscience, part of Bio-Techne | Catalog # 6411

Key Product Details

Biological Activity for tBPC

Technical Data for tBPC

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for tBPC

Product Documents for tBPC

COA

Certificate of Analysis

SDS

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