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Talniflumate

Calcium-activated Chloride Channel Blockers Small Molecule

Key Product Details

Description: CaCC blocker and Cl-/HCO3- exchange inhibitor
Chemical Name: 2-[[3-(Trifluoromethyl)phenyl]amino]-1,3-dihydro-3-oxo-1-isobenzofuranyl 3-pyridinecarboxylic acid ester
Purity: ≥99% (HPLC)
Molecular Weight: 414.34

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  • Activity evaluation of Talniflumate carried out.
    Name: Anonymous
    Species: Human
    Activity evaluation of Talniflumate carried out. Human pancreatic cancer cell line MIA PaCa and BxPC-3 were used.
    Cells were were incubated with different concentrations of Talniflumate (50, 100, 150 and 200 mkM), gefitinib and the combination of talniflumate and gefitinib for 24h.

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