Spinorphin

Name: Spinorphin
Brand: Tocris Bioscience
SKU: 2931

Tocris Bioscience, part of Bio-Techne | Catalog # 2931

COA / SDS

Enkephalin-degrading and ACE inhibitor

Discontinued Product

2931 has been discontinued. View all ACE Inhibitors products.

Key Product Details

Description:	Enkephalin-degrading and ACE inhibitor
Molecular Weight:	877.05

View Full Technical Details for Spinorphin

Technical Data
Citations

Biological Activity for Spinorphin

Spinorphin is an endogenous peptide; inhibits enkephalin-degrading enzymes (aminopeptidase, dipeptidyl aminopeptidase III, neprilysin) and angiotensin-converting enzyme. Displays antinociceptive effects in mice.

Technical Data for Spinorphin

M. Wt	877.05
Formula	C₄₅H₆₄N₈O₁₀
Single Letter Sequence	LVVYPWT
Storage	Desiccate at -20°C
CAS Number	137201-62-8
PubChem ID	3081832
InChi Key	BXIFNVGZIMFBQB-DYDSHOKNSA-N
Smiles	[H]N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H]([C@@H](C)O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Spinorphin

References are publications that support the biological activity of the product.

Liang The endogenous opioid spinorphin blocks fMet-Leu-Phe-induced neutrophil chemotaxis by acting as a specific antagonist at the N-formylpeptide receptor subtype FPR. J.Immunol. 2001 PMID: 11714831
Honda Spinorphin, an endogenous inhibitor of enkephalin-degrading enzymes, potentiates Leu-enkephalin-induced anti-allodynic and antinociceptive effects in mice. Jpn.J.Pharmacol. 2001 PMID: 11829145

Spinorphin

Tocris Bioscience, part of Bio-Techne | Catalog # 2931

Key Product Details

Biological Activity for Spinorphin

Technical Data for Spinorphin

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Spinorphin

Product Documents for Spinorphin

COA

Certificate of Analysis

SDS

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