Sarcosine

Name: Sarcosine
Brand: Tocris Bioscience
SKU: 2975

Tocris Bioscience a Bio-Techne Brand

Catalog # 2975

Citations (1)

COA / SDS

Discontinued Product

2975 has been discontinued. View all Glycine Transporter Inhibitors products.

Key Product Details

Description:	GlyT1 inhibitor
Chemical Name:	N-Methylglycine
Molecular Weight:	89.09

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Biological Activity for Sarcosine

Sarcosine is an endogenous inhibitor of GlyT1 that displays antipsychotic activity. Potentiates the action of glycine on the NMDA glycine binding site.

Technical Data for Sarcosine

M. Wt	89.09
Formula	C₃H₇NO₂
Storage	Store at RT
CAS Number	107-97-1
PubChem ID	1088
InChi Key	FSYKKLYZXJSNPZ-UHFFFAOYSA-N
Smiles	OC(CNC)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Sarcosine

Solubility

Soluble Soluble to 100 mM in water

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References for Sarcosine

References are publications that support the biological activity of the product.

Singh and Singh Meta-analysis of the efficacy of adjunctive NMDA receptor modulators in chronic schizophrenia. CNS Drugs. 2011 PMID: 21936588
Tsai Glycine transporter I inhibitor, N-methylglycine (Sarcosine), added to antipsychotics for the treatment of schizophrenia. Biol.Psychiatry 2004 PMID: 15023571

Citations for Sarcosine (1)

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Citations are publications that use Bio-Techne products. Selected citations for Sarcosine include:

Yoshikawa et al. (2012) Glycine transporter type 2 (GlyT2) inhibitor ameliorates bladder overactivity and nociceptive behavior in rats. Eur Urol. 62:704
PMID: 22341128

There are no citations that match your criteria.