Pseudo RACK1

Name: Pseudo RACK1
Brand: Tocris Bioscience
SKU: 1790

Tocris Bioscience, part of Bio-Techne | Catalog # 1790

COA / SDS

Protein kinase C activator peptide (attached to cell permeable vector)

Discontinued Product

1790 has been discontinued. View all Protein Kinase C Activators products.

Key Product Details

Description:	Protein kinase C activator peptide (attached to cell permeable vector)
Molecular Weight:	3198.81

View Full Technical Details for Pseudo RACK1

Technical Data
Citations

Biological Activity for Pseudo RACK1

Pseudo RACK1 is an activator of protein kinase C; attached to cell permeabilization Antennapedia domain vector peptide. Consists of peptide derived from the C2 domain of PKC β linked by a disulfide bridge to the Antennapedia domain vector peptide. The Antennapedia peptide is actively taken up by intact cells, at 4 or 37°C, ensuring rapid and effective uptake of the activator peptide. Once inside the cell, the disulfide bonds are subjected to reduction in the cytoplasm leading to release of the activator peptide.

Technical Data for Pseudo RACK1

M. Wt	3198.81
Formula	C₁₄₄H₂₂₅N₄₃O₃₄S₃
Single Letter Sequence	KKWKMRRNQFWIKIQRC CSVEIWD* (Modifcations: Disulfide bridge between 17 -1*)
Storage	Store at -20°C
PubChem ID	90488710
InChi Key	LTAVZZKCZYNJEE-PMCSTDROSA-N
Smiles	[H]N[C@@H](CSSC[C@H](N[H])C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(O)=O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Pseudo RACK1

References are publications that support the biological activity of the product.

Ron and Mochly-Rosen An autoregulatory region in protein kinase C: the pseudoanchoring site. Proc.Natl.Acad.Sci.U.S.A. 1995 PMID: 7831317
Theodore Intraneuronal delivery of protein kinase C pseudosubstrate leads to growth cone collapse. J.Neurosci. 1995 PMID: 7472470
Derossi The third helix of the antennapedia homeodomain translocates through biological membranes. J.Biol.Chem. 1994 PMID: 8144628

Pseudo RACK1

Tocris Bioscience, part of Bio-Techne | Catalog # 1790

Key Product Details

Biological Activity for Pseudo RACK1

Technical Data for Pseudo RACK1

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Pseudo RACK1

Product Documents for Pseudo RACK1

COA

Certificate of Analysis

SDS

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