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Parthenolide

Additional 5-HT-Related Compounds Small Molecule
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0610/100

Key Product Details

Description: 5-HT release inhibitor
Chemical Name: [1aR-(1aR*,4E,7aS*,10aS*,-10bR*)]-2,3-6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
Purity: ≥98% (HPLC)
Molecular Weight: 248.32

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  • Parthenolide as a behavioral cocaine antagonist
    Name: One Pagan
    Species: Other
    Assay Type: In Vivo
    Behavioral evaluation of antagonistic effects of parthenolide on cocaine effects in planarians
    I have used Tocris’ Parthenolide (Cat. No. 0610) for a few years in my research program searching for behavioral antagonists of cocaine. This research has resulted in 5 peer-reviewed papers and the discovery story is included in a chapter of my book The First Brain: The Neuroscience of Planarians and in a review paper (shown in the figure). There are at least 4 more papers in preparation and the project is still going strong. In the initial phases of my project, I evaluated several suppliers of parthenolide and Tocris’ offering consistently came ahead in terms of customer service and compound purity, and I do not intend to change suppliers. I recommend this product and the company without reservation.
    Parthenolide Serum 0610

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