PALDA

Name: PALDA
Brand: Tocris Bioscience
SKU: 2203

Tocris Bioscience, part of Bio-Techne | Catalog # 2203

COA / SDS

Endogenous lipid; potentiates effects of endovanilloids at TRPV1 receptors

Discontinued Product

2203 has been discontinued. View all Additional TRPV Compounds products.

Key Product Details

Description:	Endogenous lipid; potentiates effects of endovanilloids at TRPV1 receptors
Alternative Names:	N-Palmitoyldopamine
Chemical Name:	N-[2-(3,4-Dihydroxyphenyl)ethyl]hexadecanamide
Purity:	≥98% (HPLC)
Molecular Weight:	391.59

View Full Technical Details for PALDA

Technical Data
Citations

Biological Activity for PALDA

Endogenous fatty acid dopamide that displays 'entourage' effects on endovanilloids NADA and anandamide. Inactive at TRPV1 and CB₁ receptors (at concentrations up to 5 μM) and does not inhibit AMT or FAAH (IC₅₀ > 25 μM). However, potentiates TRPV1-mediated effects of NADA; lowers EC₅₀ from ~ 90 to ~ 30 nM.

Technical Data for PALDA

M. Wt	391.59
Formula	C₂₄H₄₁NO₃
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	136181-87-8
PubChem ID	16759163
InChi Key	TWJJFOWLTIEYFO-UHFFFAOYSA-N
Smiles	CCCCCCCCCCCCCCCC(=O)NCCC1=CC(O)=C(O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for PALDA

References are publications that support the biological activity of the product.

De Petrocellis Actions of two naturally occurring saturated N-acylDAs on transient receptor potential vanilloid 1 (TRPV1) channels. Br.J.Pharmacol. 2004 PMID: 15289293
Chu N-OleoylDA, a novel endogenous capsaicin-like lipid that produces hyperalgesia. J.Biol.Chem. 2003 PMID: 12569099

PALDA

Tocris Bioscience, part of Bio-Techne | Catalog # 2203

Key Product Details

Biological Activity for PALDA

Technical Data for PALDA

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for PALDA

Product Documents for PALDA

COA

Certificate of Analysis

SDS

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