[Orn⁵]-URP

Name: [Orn 5 ]-URP
Brand: Tocris Bioscience
SKU: 3162

Tocris Bioscience, part of Bio-Techne | Catalog # 3162

Citations (7)

COA / SDS

Urotensin-II (UT) receptor antagonist

Discontinued Product

3162 has been discontinued. View all Urotensin-II Receptor Antagonists products.

Key Product Details

Description:	Urotensin-II (UT) receptor antagonist
Molecular Weight:	1003.2

View Full Technical Details for [Orn⁵]-URP

Technical Data
Citations

Biological Activity for [Orn⁵]-URP

[Orn⁵]-URP is an urotensin-II (UT) receptor pure antagonist (pEC₅₀ = 7.24). Displays no agonist activity unlike other U-II/URP analogs. Inhibits the action of U-II in the rat aorta ring assay.

Technical Data for [Orn⁵]-URP

M. Wt	1003.2
Formula	C₄₈H₆₂N₁₀O₁₀S₂
Single Letter Sequence	ACFWXYCV (Modifications: X = Orn, Disulfide bridge between 2 - 7)
Storage	Store at -20°C
CAS Number	782485-03-4
PubChem ID	90488807
InChi Key	BPLKRLYKWHXTMO-LSKWFVNGSA-N
Smiles	[H]N[C@@H](C)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](CC2=CC=C(O)C=C2)NC(=O)[C@H](CCCN)NC(=O)[C@H](CC2=CNC3=C2C=CC=C3)NC(=O)[C@H](CC2=CC=CC=C2)NC1=O)C(=O)N[C@@H](C(C)C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for [Orn⁵]-URP

References are publications that support the biological activity of the product.

Diallo [Orn⁵]URP acts as a pure antagonist of urotensinergic receptors in rat cortical astrocytes. Peptides 2008 PMID: 18082287
Chatenet Structure-activity relationships and structural conformation of a novel urotensin II-related peptide. Peptides 2004 PMID: 15476952

[Orn⁵]-URP

Tocris Bioscience, part of Bio-Techne | Catalog # 3162

Key Product Details

Biological Activity for [Orn⁵]-URP

Technical Data for [Orn⁵]-URP

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for [Orn⁵]-URP

Product Documents for [Orn⁵]-URP

COA

Certificate of Analysis

SDS

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[Orn5]-URP

Tocris Bioscience, part of Bio-Techne | Catalog # 3162

Key Product Details

Biological Activity for [Orn5]-URP

Technical Data for [Orn5]-URP

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for [Orn5]-URP

Product Documents for [Orn5]-URP

COA

Certificate of Analysis

SDS

[Orn⁵]-URP

Biological Activity for [Orn⁵]-URP

Technical Data for [Orn⁵]-URP

References for [Orn⁵]-URP

Product Documents for [Orn⁵]-URP