[Orn⁵]-URP

Name: [Orn 5 ]-URP
Brand: Tocris Bioscience
SKU: 3162

Tocris Bioscience a Bio-Techne Brand

Catalog # 3162

Citations (1)

COA / SDS

Discontinued Product

3162 has been discontinued. View all Urotensin-II Receptor Antagonists products.

Key Product Details

Description:	Urotensin-II (UT) receptor antagonist
Molecular Weight:	1003.2

View Full Technical Details for [Orn⁵]-URP

Biological Activity for [Orn⁵]-URP

[Orn⁵]-URP is an urotensin-II (UT) receptor pure antagonist (pEC₅₀ = 7.24). Displays no agonist activity unlike other U-II/URP analogs. Inhibits the action of U-II in the rat aorta ring assay.

Technical Data for [Orn⁵]-URP

M. Wt	1003.2
Formula	C₄₈H₆₂N₁₀O₁₀S₂
Single Letter Sequence	ACFWXYCV (Modifications: X = Orn, Disulfide bridge between 2 - 7)
Storage	Store at -20°C
CAS Number	782485-03-4
PubChem ID	90488807
InChi Key	BPLKRLYKWHXTMO-LSKWFVNGSA-N
Smiles	[H]N[C@@H](C)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](CC2=CC=C(O)C=C2)NC(=O)[C@H](CCCN)NC(=O)[C@H](CC2=CNC3=C2C=CC=C3)NC(=O)[C@H](CC2=CC=CC=C2)NC1=O)C(=O)N[C@@H](C(C)C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for [Orn⁵]-URP

Solubility

Soluble to 1mg/ml in water

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References for [Orn⁵]-URP

References are publications that support the biological activity of the product.

Diallo [Orn⁵]URP acts as a pure antagonist of urotensinergic receptors in rat cortical astrocytes. Peptides 2008 PMID: 18082287
Chatenet Structure-activity relationships and structural conformation of a novel urotensin II-related peptide. Peptides 2004 PMID: 15476952

Citations for [Orn⁵]-URP (1)

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Citations are publications that use Bio-Techne products. Selected citations for [Orn⁵]-URP include:

Lee et al. (2014) Urotensin II induces interleukin 8 expression in human umbilical vein endothelial cells. PLoS One. 9:e90278
PMID: 24587311

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Product Documents for [Orn⁵]-URP

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.

[Orn⁵]-URP

Tocris Bioscience a Bio-Techne Brand

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References for [Orn⁵]-URP

Citations for [Orn⁵]-URP (1)

Product Documents for [Orn⁵]-URP

COA

Certificate of Analysis

SDS

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[Orn5]-URP

Tocris Bioscience a Bio-Techne Brand

Key Product Details

Customers also Viewed

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Biological Activity for [Orn5]-URP

Technical Data for [Orn5]-URP

Solubility for [Orn5]-URP

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for [Orn5]-URP

Citations for [Orn5]-URP (1)

Product Documents for [Orn5]-URP

COA

Certificate of Analysis

SDS

Bio-Techne Brands

[Orn⁵]-URP

Biological Activity for [Orn⁵]-URP

Technical Data for [Orn⁵]-URP

Solubility for [Orn⁵]-URP

References for [Orn⁵]-URP

Citations for [Orn⁵]-URP (1)

Product Documents for [Orn⁵]-URP