Oleamide

Name: Oleamide
Brand: tocris
SKU: 0878

Catalog # 0878

Datasheet / COA / SDS

Order Information

Bio-Techne Corporation

tel: (612) 379-2956

tel: (800) 343-7475 (free phone)

customercare.na@bio-techne.com

Shipping Information

$35 to United States

Products in stock will be shipped in 1-3 business days unless specified.

View Distributors

Key Product Details

Description:	Sleep-inducing brain lipid
Chemical Name:	cis-9-Octadecenamide
Purity:	≥98%

View Full Technical Details for Oleamide

Complete Your Experiment

Biological Activity

Endogenous sleep-inducing lipid. Acts as an agonist at the CB₁ cannabinoid receptor (EC₅₀ = 1.64 μM). Also appears to potentiate the actions of 5-HT on 5-HT_2A and _2C receptors, and act via an allosteric regulatory site on 5-HT₇ receptors.

Technical Data

M. Wt	281.48
Formula	C₁₈H₃₅NO
Storage	Store at +4°C
Purity	≥98%
CAS Number	301-02-0
PubChem ID	5283387
InChi Key	FATBGEAMYMYZAF-KTKRTIGZSA-N
Smiles	CCCCCCCC\C=C/CCCCCCCC(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	ethanol	28.15	100
	DMSO	14.07	50

Preparing Stock Solutions

The following data is based on the product molecular weight 281.48.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.55 mL	17.76 mL	35.53 mL
5 mM	0.71 mL	3.55 mL	7.11 mL
10 mM	0.36 mL	1.78 mL	3.55 mL
50 mM	0.07 mL	0.36 mL	0.71 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References

References are publications that support the biological activity of the product.

Cravatt Chemical characterisation of a family of brain lipids that induces sleep. Science 1995 PMID: 7770779
Hedlund Allosteric regulation by oleamide of the binding properties of 5-hydroxytryptamine₇ receptors. Biochem.Pharmacol. 1999 PMID: 10571256
Huidobro-Toro and Harris Brain lipids that induce sleep are novel modulators of 5-hydroxytryptamine receptors. Proc.Natl.Acad.Sci.U.S.A. 1996 PMID: 8755606
Leggett Oleamide is a selective endogenous agonist of rat and human CB₁ cannabinoid receptors. Br.J.Pharmacol. 2004 PMID: 14707029