NGD 94-1

Name: NGD 94-1
Brand: Tocris Bioscience
SKU: 3298

Tocris Bioscience, part of Bio-Techne | Catalog # 3298

COA / SDS

Selective D4 receptor ligand

Discontinued Product

3298 has been discontinued. View all Dopamine D4 Receptor Ligands products.

Key Product Details

Description:	Selective D₄ receptor ligand
Chemical Name:	2-[4-[(2-Phenyl-1H-imidazol-5-yl)methyl]-1-piperazinyl]-pyrimidine
Purity:	≥99% (HPLC)
Molecular Weight:	320.39

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Technical Data
Citations

Biological Activity for NGD 94-1

High affinity D₄ receptor ligand; selective over D₁, D₂, D₃ and D₅ receptors. Displays antagonist activity at the human D_4.2 receptor (K_i = 3.6 nM in transfected CHO cells) and exhibits agonist activity at the D_4.4 receptor in HEK 293 cells.

Technical Data for NGD 94-1

M. Wt	320.39
Formula	C₁₈H₂₀N₆
Storage	Store at +4°C
Purity	≥99% (HPLC)
CAS Number	178928-68-2
PubChem ID	188942
InChi Key	OTVQCHUIPJYASM-UHFFFAOYSA-N
Smiles	C1(N2CCN(CC3=CN=C(C4=CC=CC=C4)N3)CC2)=NC=CC=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for NGD 94-1

References are publications that support the biological activity of the product.

Primus II. Localization and characterization of DA D₄ binding sites in rat and human brain by use of the novel, D₄ receptor-selective ligand [³H]NGD 94-1. J.Pharmacol.Exp.Ther. 1997 PMID: 9262371
Gazi NGD 94-1 as an agonist at human recombinant DA D_4.4 receptors expressed in HEK293 cells. Eur.J.Pharmacol. 1999 PMID: 10395031
Tallman I. NGD 94-1: Identification of a novel, high affinity antagonist at the human DA D₄ receptor. J.Pharmacol.Exp.Ther. 1997 PMID: 9262370

NGD 94-1

Tocris Bioscience, part of Bio-Techne | Catalog # 3298

Key Product Details

Biological Activity for NGD 94-1

Technical Data for NGD 94-1

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for NGD 94-1

Product Documents for NGD 94-1

COA

Certificate of Analysis

SDS

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