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Key Product Details
| Description: | 5-HT2C antagonist |
| Alternative Names: | Normethylclozapine, Norclozapine |
| Chemical Name: | 8-Chloro-11-(1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine |
| Purity: | ≥99% (HPLC) |
| Molecular Weight: | 312.8 |
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Citations (3)
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Citations are publications that use Bio-Techne products. Selected citations for N-Desmethylclozapine include:
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Gregory et al.
(2010)
Identification of orthosteric and allosteric site mutations in M2 muscarinic acetylcholine receptors that contribute to ligand-selective signaling bias.
J Biol Chem.
285:7459
PMID: 20051519 -
Magliaro and Saldanha
(2009)
Clozapine protects PC-12 cells from death due to oxidative stress induced by hydrogen peroxide via a cell-type specific mechanism involving inhibition of extracellular signal-regulated kinase phosphorylation.
Brain Res.
1283:14
PMID: 19501068 -
Sur et al.
(2003)
N-desmethylclozapine, an allosteric agonist at muscarinic 1 receptor, potentiates N-MthD.-aspartate receptor activity.
Proc Natl Acad Sci U S A.
100:13674
PMID: 14595031
There are no citations that match your criteria.
