ML 161

Name: ML 161
Brand: Tocris Bioscience
SKU: 4570

Tocris Bioscience, part of Bio-Techne | Catalog # 4570

COA / SDS

Inhibits PAR1-mediated platelet activation

Discontinued Product

4570 has been discontinued. View all Protease-Activated Receptor Inhibitors products.

Key Product Details

Description:	Inhibits PAR₁-mediated platelet activation
Chemical Name:	2-Bromo-N-[3-[(1-oxobutyl)amino]phenyl]benzamide
Purity:	≥98% (HPLC)
Molecular Weight:	361.23

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Technical Data
Citations

Biological Activity for ML 161

ML 161 is an inhibitor of protease-activated receptor 1 (PAR₁)-mediated platelet activation (IC₅₀ = 0.26 μM for the inhibition of platelet P-selectin expression on human platelets). Thought to act allosterically. Also inhibits thrombin-induced platelet activation.

Technical Data for ML 161

M. Wt	361.23
Formula	C₁₇H₁₇BrN₂O₂
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	423735-93-7
PubChem ID	1048267
InChi Key	DFOVLSMXPWPCFH-UHFFFAOYSA-N
Smiles	O=C(NC2=CC(NC(CCC)=O)=CC=C2)C1=CC=CC=C1Br

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for ML 161

References are publications that support the biological activity of the product.

Dockendorff Discovery of 1,3-diaminobenzenes as selective inhibitors of platelet activation at the PAR1 receptor. ACS Med.Chem.Lett. 2012 PMID: 22408714

ML 161

Tocris Bioscience, part of Bio-Techne | Catalog # 4570

Key Product Details

Biological Activity for ML 161

Technical Data for ML 161

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for ML 161

Product Documents for ML 161

COA

Certificate of Analysis

SDS

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