Ipratropium bromide

Name: Ipratropium bromide
Brand: Tocris Bioscience
SKU: 0692

Catalog # 0692

Citations (3)

COA / SDS

Discontinued Product

0692 has been discontinued. View all Non-selective mAChR Antagonists products.

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$35 to United States

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Key Product Details

Description:	Muscarinic antagonist
Chemical Name:	(endo,syn)-(±)-3-(3-Hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-8-azoniabicyclo[3.2.1]octane bromide
Purity:	≥98% (HPLC)
Molecular Weight:	412.37

View Full Technical Details for Ipratropium bromide

Biological Activity

Ipratropium bromide is a muscarinic antagonist, bronchodilator. N-Isopropyl salt of atropine.

Technical Data

M. Wt	412.37
Formula	C₂₀H₃₀BrNO₃
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	22254-24-6
PubChem ID	31098
InChi Key	LHLMOSXCXGLMMN-UHFFFAOYSA-M
Smiles	O=C(C(CO)C3=CC=CC=C3)O[C@@H]1CC2CCC([N+](C)2C(C)C)C1.[Br-]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	20.62	50

Preparing Stock Solutions

The following data is based on the product molecular weight 412.37.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	4.85 mL	24.25 mL	48.50 mL
2.5 mM	0.97 mL	4.85 mL	9.70 mL
5 mM	0.49 mL	2.43 mL	4.85 mL
25 mM	0.10 mL	0.49 mL	0.97 mL

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Reconstitution Calculator

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References

References are publications that support the biological activity of the product.

Fryer and Maclagan Ipratropium bromide potentiates bronchoconstriction induced by vagal nerve stimulation in the guinea-pig. Eur.J.Pharmacol. 1987 PMID: 2958300

Citations for Ipratropium bromide (3)

Showing 1 - 3 of 3 citations Showing All

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Citations are publications that use Bio-Techne products. Selected citations for Ipratropium bromide include:

Valeria et al. (2016) A subnanomolar concentration of Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) pre-synaptically modulates glutamatergic transmission in the rat hippocampus acting through acetylcholine Neuroscience. 340:551
PMID: 27816700
Deng et al. (2013) Label-free cell phenotypic assessment of the biased agonism and efficacy of agonists at the endogenous muscarinic M3 receptors. J Pharmacol Toxicol Methods. 68:323
PMID: 23933114
Woo et al. (2007) Neuregulin-1 enhances depolarization-induced GABA release. Neuron. 54:599
PMID: 17521572

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