Ipratropium bromide

Name: Ipratropium bromide
Brand: tocris
SKU: 0692

Catalog # 0692

Citations (3)

Datasheet / COA / SDS

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Key Product Details

Description:	Muscarinic antagonist
Chemical Name:	(endo,syn)-(±)-3-(3-Hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-8-azoniabicyclo[3.2.1]octane bromide
Purity:	≥98% (HPLC)
Molecular Weight:	412.37

View Full Technical Details for Ipratropium bromide

Biological Activity

Muscarinic antagonist, bronchodilator. N-Isopropyl salt of atropine.

Technical Data

M. Wt	412.37
Formula	C₂₀H₃₀BrNO₃
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	22254-24-6
PubChem ID	31098
InChi Key	LHLMOSXCXGLMMN-UHFFFAOYSA-M
Smiles	O=C(C(CO)C3=CC=CC=C3)O[C@@H]1CC2CCC([N+](C)2C(C)C)C1.[Br-]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	20.62	50

Preparing Stock Solutions

The following data is based on the product molecular weight 412.37.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	4.85 mL	24.25 mL	48.50 mL
2.5 mM	0.97 mL	4.85 mL	9.70 mL
5 mM	0.49 mL	2.43 mL	4.85 mL
25 mM	0.10 mL	0.49 mL	0.97 mL

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References

References are publications that support the biological activity of the product.

Fryer and Maclagan Ipratropium bromide potentiates bronchoconstriction induced by vagal nerve stimulation in the guinea-pig. Eur.J.Pharmacol. 1987 PMID: 2958300
Merck Index

Citations (3)

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Citations are publications that use Bio-Techne products. Selected citations for Ipratropium bromide include:

Valeria et al. (2016) A subnanomolar concentration of Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) pre-synaptically modulates glutamatergic transmission in the rat hippocampus acting through acetylcholine Neuroscience. 340:551
PMID: 27816700
Deng et al. (2013) Label-free cell phenotypic assessment of the biased agonism and efficacy of agonists at the endogenous muscarinic M3 receptors. J Pharmacol Toxicol Methods. 68:323
PMID: 23933114
Woo et al. (2007) Neuregulin-1 enhances depolarization-induced GABA release. Neuron. 54:599
PMID: 17521572

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Product Datasheets

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.

Ipratropium bromide

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Key Product Details

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Biological Activity

Technical Data

Solubility

Preparing Stock Solutions

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References

Citations (3)

Product Datasheets

COA

Certificate of Analysis

SDS

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