Homoquinolinic acid

Name: Homoquinolinic acid
Brand: tocris
SKU: 0197

Catalog # 0197

Datasheet / COA / SDS

Discontinued Product

0197 has been discontinued. View all NMDA Receptor Agonists products.

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Bio-Techne Corporation

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tel: (800) 343-7475 (free phone)

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$35 to United States

Products in stock will be shipped in 1-3 business days unless specified.

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Key Product Details

Description:	Potent and selective NMDA agonist
Purity:	≥99% (HPLC)
Molecular Weight:	181.15

View Full Technical Details for Homoquinolinic acid

Technical Data
Citations / Reviews

Biological Activity

Potent NMDA receptor agonist; subtype-selective.

Technical Data

M. Wt	181.15
Formula	C₈H₇NO₄
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	490-75-5
PubChem ID	3080554
InChi Key	HQPMJFFEXJELOQ-UHFFFAOYSA-N
Smiles	OC(=O)CC1=CC=CN=C1C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	1eq. NaOH		100

Preparing Stock Solutions

The following data is based on the product molecular weight 181.15.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	5.52 mL	27.60 mL	55.20 mL
5 mM	1.10 mL	5.52 mL	11.04 mL
10 mM	0.55 mL	2.76 mL	5.52 mL
50 mM	0.11 mL	0.55 mL	1.10 mL

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Reconstitution Calculator

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References

References are publications that support the biological activity of the product.

Olverman Structure/activity relations of NMDA receptor ligands as studied by their inhibition of [³H]-D-2-amino-5-phosphonopentanoic acid binding in rat brain membranes. Neuroscience 1988 PMID: 2901691
Prado de Carvalho The endogenous agonist quinolinic acid and the non-endogenous homoquinolinic acid discriminate between NMDAR2 receptors subunits. Neurochem.Int. 1996 PMID: 8740453
Stone Excitant activity of methyl derivatives of quinolinic acid on rat cortical neurones. Br.J.Pharmacol. 1984 PMID: 6546701