Hemopressin (human, mouse)

Name: Hemopressin (human, mouse)
Brand: Tocris Bioscience
SKU: 3791
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 3791

(1)

Citations (2)

COA / SDS

Selective CB1 inverse agonist

Key Product Details

Description:	Selective CB₁ inverse agonist
Molecular Weight:	1054.26

View Full Technical Details for Hemopressin (human, mouse)

Technical Data
Citations / Reviews (1)

Biological Activity for Hemopressin (human, mouse)

Hemopressin (human, mouse) is a bioactive endogenous peptide substrate for endopeptidase 24.15 (ep24.15), neurolysin (ep24.16) and ACE. K_i values are 27.76, 3.43 and 1.87 μM respectively. Potent hypotensive in vivo. Also acts as a selective CB₁ receptor inverse agonist. Displays antinociceptive activity in vivo.

Technical Data for Hemopressin (human, mouse)

M. Wt	1054.26
Formula	C₅₀H₇₉N₁₃O₁₂
Single Letter Sequence	PVNFKLLSH
Storage	Store at -20°C
CAS Number	1314035-51-2
PubChem ID	90488877
InChi Key	JEXQOFXDPAGOQL-TZFLQVIRSA-N
Smiles	[H]N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CNC=N1)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Hemopressin (human, mouse)

Solubility

Soluble to 1mg/ml in water

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References for Hemopressin (human, mouse)

References are publications that support the biological activity of the product.

Blais Hypotensive effects of hemopressin and bradykinin in rabbits, rats and mice. A comparative study. Peptides 2005 PMID: 16042973
Heimann Hemopressin is an inverse agonist of CB₁ cannabinoid receptors. Proc.Natl.Acad.Sci.USA
Rioli Novel natural peptide substrates for endopeptidase 24.15, neurolysin, and angiotensin-converting enzyme. J.Biol.Chem. 2003 PMID: 12500972