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Key Product Details
| Description: | Protein kinase inhibitor |
| Chemical Name: | (±)-1-(5-Isoquinolinesulphonyl)-2-methylpiperazine dihydrochloride |
| Purity: | ≥99% (HPLC) |
Showing 1-4 of 4 citations
Citations (4)
Citations are publications that use Bio-techne products. Selected citations for H-7 dihydrochloride include:
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Zhao et al.
(2018)
TRPV4 Blockade Preserves the Blood-Brain Barrier by Inhibiting Stress Fiber Formation in a Rat Model of Intracerebral Hemorrhage.
Front Mol Neurosci.
11:97
PMID: 29636662 -
Barcomb et al.
(2013)
Enzymatic activity of CaMKII is not required for its interaction with the glutamate receptor subunit GluN2B.
Front Mol Neurosci.
84:834
PMID: 24056996 -
Ludgate et al.
(2012)
Cyclin-dependent kinase 2 phosphorylates s/t-p sites in the hepadnavirus core protein C-terminal domain and is incorporated into viral capsids.
J Virol.
86:12237
PMID: 22951823 -
Belmeguenai and Hansel
(2005)
A role for protein phosphatases 1, 2A, and 2B in cerebellar long-term potentiation.
Mol Pharmacol.
25:10768
PMID: 16291950
There are no citations that match your criteria.
Customer Reviews
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H7 was studied for its inhibitory role in cAMP dependent protein kinase
Species: HumanH7 was studied for its inhibitory role in cAMP dependent protein kinase with ICso values of 18 and 16 gM respectively.Cultures were incubated for 16 hours at 37 ~ in an atmosphere of 5% CO2 and 95% humidified air. 1~tCi of [3H]-thymidine was added to each well and cultures incubated for a further 5 hours. Cells were then harvested onto glass fibre filters, washed and incorporated radioactivity determined by liq- uid scintillation spectrometry.
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