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H-7 dihydrochloride

Broad Spectrum Protein Kinase Inhibitors Small Molecule

Key Product Details

Description: Protein kinase inhibitor
Chemical Name: (±)-1-(5-Isoquinolinesulphonyl)-2-methylpiperazine dihydrochloride
Purity: ≥99% (HPLC)
Molecular Weight: 364.29

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  • H7 was studied for its inhibitory role in cAMP dependent protein kinase
    Name: Anonymous
    Species: Human
    H7 was studied for its inhibitory role in cAMP dependent protein kinase with ICso values of 18 and 16 gM respectively.
    Cultures were incubated for 16 hours at 37 ~ in an atmosphere of 5% CO2 and 95% humidified air. 1~tCi of [3H]-thymidine was added to each well and cultures incubated for a further 5 hours. Cells were then harvested onto glass fibre filters, washed and incorporated radioactivity determined by liq- uid scintillation spectrometry.
    H-7 dihydrochloride Serum 0542

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