Golgicide A

Name: Golgicide A
Brand: Tocris Bioscience
SKU: 3584

Tocris Bioscience, part of Bio-Techne | Catalog # 3584

Citations (13)

COA / SDS

Potent, selective and reversible inhibitor of GBF1 ArfGEF

Discontinued Product

3584 has been discontinued. View all ARF GTPase Inhibitors products.

Key Product Details

Description:	Potent, selective and reversible inhibitor of GBF1 ArfGEF
Chemical Name:	6,8-Difluoro-4-pyridin-3-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline
Purity:	≥98% (HPLC)
Molecular Weight:	284.3

View Full Technical Details for Golgicide A

Technical Data
Citations

Biological Activity for Golgicide A

Golgicide A is a potent, specific and reversible inhibitor of Golgi BFA resistance factor 1 (GBF1), an ArfGEF, that decreases Arf1 activation in vivo. Arrests secretion of soluble and membrane-associated proteins at the endoplasmic reticulum-Golgi intermediate compartment. Causes disassembly and dispersal of the Golgi and trans-Golgi network.

Technical Data for Golgicide A

M. Wt	284.3
Formula	C₁₇H₁₄F₂N₂
Storage	Store at RT
Purity	≥98% (HPLC)
CAS Number	1139889-93-2
PubChem ID	25113626
InChi Key	NJZHEQOUHLZCOX-FTLRAWMYSA-N
Smiles	FC4=CC([C@]3([H])[C@]([H])2CC=C3)=C(C(F)=C4)NC2C1=CN=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Golgicide A

References are publications that support the biological activity of the product.

Saenz Golgicide A reveals essential roles for GBF1 in Golgi assembly and function. Nature Chem.Biol.

Golgicide A

Tocris Bioscience, part of Bio-Techne | Catalog # 3584

Key Product Details

Biological Activity for Golgicide A

Technical Data for Golgicide A

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Golgicide A

Product Documents for Golgicide A

COA

Certificate of Analysis

SDS

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