FGIN-1-43

Name: FGIN-1-43
Brand: tocris
SKU: 0659

Catalog # 0659

Datasheet / COA / SDS

Discontinued Product

0659 has been discontinued. View all Other Translocator Protein Compounds products.

Order Information

Bio-Techne Corporation

tel: (800) 343-7475 (free phone)

tel: (612) 379-2956

customercare.na@bio-techne.com

Shipping Information

$35 to United States

Products in stock will be shipped in 1-3 business days unless specified.

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Key Product Details

Description:	Potent, specific ligand for mitochondrial DBI receptor
Chemical Name:	N,N-Dihexyl-2-(4-chlorophenyl)-5-chloroindole-3-acetamide
Purity:	≥98%
Molecular Weight:	487.51

View Full Technical Details for FGIN-1-43

Biological Activity

Most active of the 2-aryl-3-indoleacetamides; a new class of potent and specific ligands as probes for the mitochondial DBI receptor (peripheral benzodiazepine receptor).

Technical Data

M. Wt	487.51
Formula	C₂₈H₃₆Cl₂N₂O
Storage	Store at RT
Purity	≥98%
CAS Number	145040-29-5
PubChem ID	3995234
InChi Key	XTZUPNNVXIMWAR-UHFFFAOYSA-N
Smiles	O=C(N(CCCCCC)CCCCCC)CC2=C(C3=CC=C(Cl)C=C3)NC1=CC=C(Cl)C=C12

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	24.37	50

Preparing Stock Solutions

The following data is based on the product molecular weight 487.51.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	4.10 mL	20.51 mL	41.02 mL
2.5 mM	0.82 mL	4.10 mL	8.20 mL
5 mM	0.41 mL	2.05 mL	4.10 mL
25 mM	0.08 mL	0.41 mL	0.82 mL

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Reconstitution Calculator

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References

References are publications that support the biological activity of the product.

Kozikowski Chemistry, binding affinities, and behavioural properties of a new class of "antineophobic" mitochondrial DBI receptor (mDRC) ligands. J.Med.Chem. 1993 PMID: 8411007
Romeo 2-Aryl-3-indoleacetamides (FGIN-1): a new class of potent and specific ligands for the mitochondrial DBI receptor (MDR). J.Pharmacol.Exp.Ther. 1992 PMID: 1326631