(E)-FeCP-oxindole

Name: ( E )-FeCP-oxindole
Brand: Tocris Bioscience
SKU: 3882

Tocris Bioscience, part of Bio-Techne | Catalog # 3882

COA / SDS

Selective VEGFR-2 inhibitor

Discontinued Product

3882 has been discontinued. View all VEGF Receptor Inhibitors products.

Key Product Details

Description:	Selective VEGFR-2 inhibitor
Chemical Name:	(E)-3-Ferrocenylmethylidene-1,3-dihydro-2H-indol-2-one
Molecular Weight:	329.17

View Full Technical Details for (E)-FeCP-oxindole

Technical Data
Citations

Biological Activity for (E)-FeCP-oxindole

Selective inhibitor of human vascular endothelial cell growth factor receptor 2 (VEGFR-2) (IC₅₀ = 214 nM). Displays anticancer activity (IC₅₀μM against B16 murine melanoma lines). Does not significantly inhibit VEGFR1 or PDGFRa or b at a concentration of 10μM.

Geometric Isomer also available.

Technical Data for (E)-FeCP-oxindole

M. Wt	329.17
Formula	C₁₉H₁₅FeNO
Storage	Store at +4°C
CAS Number	884338-18-5
PubChem ID	124080971
InChi Key	JGKCUURLEMXRGX-ANOGCNOSSA-N
Smiles	[Fe++].[CH-]1C=CC=C1.O=C1NC2=CC=CC=C2\C1=C/C1=C[CH-]C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for (E)-FeCP-oxindole

References are publications that support the biological activity of the product.

Spencer Structural and biological investigation of ferrocene-substituted 3-methylidene-1,3-dihydro-2H-indol-2-ones. Dalton Transact.
Spencer Synthesis and evaluation of metallocene containing methylene-1,3-dihydro-2H-indol-2-ones as kinase inhibitors. Metallomics 2011 PMID: 21359402

(E)-FeCP-oxindole

Tocris Bioscience, part of Bio-Techne | Catalog # 3882

Key Product Details

Biological Activity for (E)-FeCP-oxindole

Technical Data for (E)-FeCP-oxindole

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for (E)-FeCP-oxindole

Product Documents for (E)-FeCP-oxindole

COA

Certificate of Analysis

SDS

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