DMeOB

Name: DMeOB
Brand: Tocris Bioscience
SKU: 1953

Tocris Bioscience, part of Bio-Techne | Catalog # 1953

COA / SDS

Negative allosteric modulator of mGlu5 receptors

Discontinued Product

1953 has been discontinued. View all Group I mGluR Modulators products.

Key Product Details

Description:	Negative allosteric modulator of mGlu₅ receptors
Chemical Name:	[(3-Methoxyphenyl)methylene]hydrazone-3-methoxybenzaldehyde
Purity:	≥98% (HPLC)
Molecular Weight:	268.31

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Technical Data
Citations

Biological Activity for DMeOB

Negative allosteric modulator of the metabotropic glutamate receptor mGlu₅; displays reversible non-competitive inhibition of mGlu₅-mediated responses (IC₅₀ = 3 μM).

Technical Data for DMeOB

M. Wt	268.31
Formula	C₁₆H₁₆N₂O₂
Storage	Store at RT
Purity	≥98% (HPLC)
CAS Number	40252-74-2
PubChem ID	9604993
InChi Key	CWHVUMNEZIBZFC-UHFFFAOYSA-N
Smiles	COC1=CC(=CC=C1)\N=C\N=C\C1=CC(OC)=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for DMeOB

References are publications that support the biological activity of the product.

O'Brien A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5 Mol.Pharmacol. 2003 PMID: 12920211

DMeOB

Tocris Bioscience, part of Bio-Techne | Catalog # 1953

Key Product Details

Biological Activity for DMeOB

Technical Data for DMeOB

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for DMeOB

Product Documents for DMeOB

COA

Certificate of Analysis

SDS

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