Dilazep dihydrochloride

Name: Dilazep dihydrochloride
Brand: tocris
SKU: 0481

Catalog # 0481

Datasheet / COA / SDS

Order Information

Bio-Techne Corporation

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$35 to United States

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Key Product Details

Description:	Adenosine uptake inhibitor
Chemical Name:	1,4-bis[3-(3,4,5-Trimethoxybenzoyloxy)propyl]homopiperazine dihydrochloride
Purity:	≥99% (HPLC)
Molecular Weight:	677.62

View Full Technical Details for Dilazep dihydrochloride

Biological Activity

Dilazep dihydrochloride is a coronary and cerebral vasodilator, suppresses the effects of ischemia. Inhibitor of platelet aggregation and of membrane transport of nucleosides. Inhibits adenosine uptake.

Technical Data

M. Wt	677.62
Formula	C₃₁H₄₄N₂O₁₀.2HCl
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	20153-98-4
PubChem ID	29976
InChi Key	VILIWRRWAWKXRW-UHFFFAOYSA-N
Smiles	Cl.Cl.COC1=CC(=CC(OC)=C1OC)C(=O)OCCCN1CCCN(CCCOC(=O)C2=CC(OC)=C(OC)C(OC)=C2)CC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water		100

Preparing Stock Solutions

The following data is based on the product molecular weight 677.62.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.48 mL	7.38 mL	14.76 mL
5 mM	0.30 mL	1.48 mL	2.95 mL
10 mM	0.15 mL	0.74 mL	1.48 mL
50 mM	0.03 mL	0.15 mL	0.30 mL

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Reconstitution Calculator

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References

References are publications that support the biological activity of the product.

Kawagoe Effect of dilazep dihydrochloride against ischemia and reperfusion-induced disruption of blood-brain barrier in rats: a quantitative study. Naunyn Schmiedebergs Arch.Pharmacol. 1992 PMID: 1620248
Zhang Dilazep potentation of adenosine-mediated superior mesenteric arterial vasodilation. J.Pharmacol.Exp.Ther. 1991 PMID: 1890619