Dihydroergocristine mesylate

Name: Dihydroergocristine mesylate
Brand: tocris
SKU: 0474

Catalog # 0474

Datasheet / COA / SDS

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Key Product Details

Description:	α partial agonist
Chemical Name:	(5'α,10α)-9,10-Dihydro-12'-hydroxy-2'-(1-methylethyl)-5'-(phenylmethyl)-ergotaman-3',6',18-trione mesylate
Purity:	≥98% (HPLC)
Molecular Weight:	707.84

View Full Technical Details for Dihydroergocristine mesylate

Biological Activity

5-HT receptor antagonist; partial agonist at adrenergic and dopaminergic receptors.

Technical Data

M. Wt	707.84
Formula	C₃₅H₄₁N₅O₅.CH₃SO₃H
Storage	Store at RT
Purity	≥98% (HPLC)
CAS Number	24730-10-7
PubChem ID	444034
InChi Key	SPXACGZWWVIDGR-SPZWACKZSA-N
Smiles	CS(=O)(O)=O.[H][C@]4([C@@]([H])3C[C@@H]([C@@](N[C@@]5([C@H](C)C)C(N([C@@]([H])(CC8=CC=CC=C8)C(N7[C@]([H])6CCC7)=O)[C@@]6(O)O5)=O)=O)CN4C)CC1=CNC2=C1C3=CC=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	17.7	25

Preparing Stock Solutions

The following data is based on the product molecular weight 707.84.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.25 mM	5.65 mL	28.25 mL	56.51 mL
1.25 mM	1.13 mL	5.65 mL	11.30 mL
2.5 mM	0.57 mL	2.83 mL	5.65 mL
12.5 mM	0.11 mL	0.57 mL	1.13 mL

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Reconstitution Calculator

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References

References are publications that support the biological activity of the product.

Drago Dihydroergocristine and memory alterations of aged male rats. Pharmacol.Biochem.Behav. 1988 PMID: 3147464