Daminozide

Name: Daminozide
Brand: Tocris Bioscience
SKU: 4684

Tocris Bioscience, part of Bio-Techne | Catalog # 4684

COA / SDS

Selective KDM2/7 inhibitor

Discontinued Product

4684 has been discontinued. View all Histone Demethylase Inhibitors products.

Key Product Details

Description:	Selective KDM2/7 inhibitor
Chemical Name:	1-(2,2-Dimethylhydrazide)butanedioic acid
Molecular Weight:	160.17

View Full Technical Details for Daminozide

Technical Data
Citations

Biological Activity for Daminozide

Daminozide is a histone demethylase KDM2/7 subfamily inhibitor (IC₅₀ values are 0.55, 1.5 and 2.1 μM for PHF8, KDM2A and KDM7A respectively). Exhibits ≥ 60-fold selectivity for KDM2/7 demethylases over other histone demethylases and 2-oxoglurate oxygenases (IC₅₀ > 100 μM).

Technical Data for Daminozide

M. Wt	160.17
Formula	C₆H₁₂N₂O₃
Storage	Store at RT
CAS Number	1596-84-5
PubChem ID	15331
InChi Key	NOQGZXFMHARMLW-UHFFFAOYSA-N
Smiles	O=C(NN(C)C)CCC(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Daminozide

References are publications that support the biological activity of the product.

Rose Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases. J.Med.Chem. 2012 PMID: 22724510

Product Documents for Daminozide

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.

SDS

⚠ WARNING: This product can expose you to chemicals including Daminozide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov