CORM 2

Name: CORM 2
Brand: Tocris Bioscience
SKU: 6117

Tocris Bioscience, part of Bio-Techne | Catalog # 6117

COA / SDS

Carbon monoxide-releasing molecule

Discontinued Product

6117 has been discontinued. View all Additional ROS Donor Products products.

Key Product Details

Description:	Carbon monoxide-releasing molecule
Chemical Name:	Tricarbonyldichlororuthenium(II) dimer
Molecular Weight:	512.01

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Technical Data
Citations

Biological Activity for CORM 2

CORM 2 is a carbon monoxide-releasing molecule. Causes vasodilatation in isolated aortic rings in vitro. Cytotoxic to smooth muscle cells in vitro after prolonged (24h) exposure. Exhibits antihypertensive effects in vivo. Reduces tight-junction disruption in intestinal mucosa in a rat sepsis model.

Technical Data for CORM 2

M. Wt	512.01
Formula	C₆Cl₄O₆Ru₂
Storage	Store at RT
CAS Number	22594-69-0
PubChem ID	10951331
InChi Key	JYHHJVKGDCZCCL-UHFFFAOYSA-J
Smiles	[Cl-][Ru++]1([Cl-][Ru++]([Cl-])([Cl-]1)(C#[O])(C#[O])C#[O])(C#[O])(C#[O])C#[O]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for CORM 2

References are publications that support the biological activity of the product.

Motterlini Carbon monoxide-releasing molecules: characterization of biochemical and vascular activities. Circ.Res. 2002 PMID: 11834719
Zhang Carbon monoxide-releasing molecule-2 reduces intestinal epithelial tight-junction damage and mortality in septic rats. PLoS One 2015 PMID: 26720630

CORM 2

Tocris Bioscience, part of Bio-Techne | Catalog # 6117

Key Product Details

Biological Activity for CORM 2

Technical Data for CORM 2

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for CORM 2

Product Documents for CORM 2

COA

Certificate of Analysis

SDS

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