Selective inhibitor of p38α-mediated MK2a phosphorylation; also tubulin polymerization inhibitor
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Key Product Details
Description: | Selective inhibitor of p38α-mediated MK2a phosphorylation; also tubulin polymerization inhibitor |
Chemical Name: | 2'-Fluoro-N-(4-hydroxyphenyl)-[1,1'-biphenyl]-4-butanamide |
Purity: | ≥99% (HPLC) |
Molecular Weight: | 349.4 |
Citations for CMPD-1 (3)
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Citations are publications that use Bio-Techne products. Selected citations for CMPD-1 include:
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Ryals et al.
(2018)
The Inner Ear Heat Shock Transcriptional Signature Identifies Compounds That Protect Against Aminoglycoside Ototoxicity.
Front Cell Neurosci.
12:445
PMID: 30532693 -
Breindel et al.
(2013)
EGF receptor activates MET through MAPK to enhance non-small cell lung carcinoma invasion and brain metastasis.
Cancer Res.
73:5053
PMID: 23794705 -
Fricke et al.
(2013)
p38 and OGT sequestration into viral inclusion bodies in cells infected with human respiratory syncytial virus suppresses MK2 activities and stress granule assembly.
J Virol.
87:1333
PMID: 23152511
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Species: OtherAssay Type: In VivoCell Line/Tissue: larvaeZebrafish larvae were placed into 48-well plates and used the DASPEI screen by 42 perturbagens drugs, including this compound
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