CCCP

Citations are publications that use Bio-Techne products. Selected citations for CCCP include:

• Guo et al. (2015) Use of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (hiPSC-CMs) to Monitor Compound Effects on Cardiac Myocyte Signaling Pathways. Curr Protoc Chem Biol. 7:141
  PMID: 26331525
• Choubey et al. (2014) BECN1 is involved in the initiation of mitophagy: it facilitates PARK2 translocation to mitochondria. Autophagy. 10:1105
  PMID: 24879156
• Purnell (2014) Efavirenz induces neuronal autophagy and mitochondrial alterations. J Pharmacol Exp Ther. 351:250
  PMID: 25161171
• Chouhan et al. (2010) Presynaptic mitochondria in functionally different motor neurons exhibit similar affinities for Ca²⁺ but exert little influence as Ca²⁺ buffers at nerve firing rates in situ. J Neurosci. 30:1869
  PMID: 20130196

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• Mitochondrial studies in live neurons

  Name: Karthik krishnamurthy
  Species: Rat
  Assay Type: In Vitro
  Cell Line/Tissue: spinal cord neurons
  TMRM fluorescence intensity before and after CCCP addition was used for the quantitation of change in mitochondrial membrane potential in spinal cord neurons induced by glutamate receptor agonist AMPA
  Time lapse images of TMRM fluorescence of mitochondria rich regions in neurons was recorded. The fluorescence intensity (F) at a given time point was normalized to the initial fluorescence intensity (F0) before addition of the AMPA. At the end of each experiment CCCP (750 nM) was added to the bath. CCCP collapses the mitochondrial membrane potential and decreases the TMRM fluorescence.
  

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