Buprenorphine hydrochloride

Name: Buprenorphine hydrochloride
Brand: Tocris Bioscience
SKU: 2808

Catalog # 2808 | Tocris Bioscience a Bio-Techne Brand

Citations (1)

COA / SDS

NOP agonist; also displays mixed action δ, κ and μ receptors

Discontinued Product

2808 has been discontinued. View all Miscellaneous/Non-selective Opioid Compounds products.

Key Product Details

Description:	NOP agonist; also displays mixed action δ, κ and μ receptors
Chemical Name:	[5α,7α(S)]-17-(Cyclopropylmethyl)-α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α-methyl-6,14-ethenomorphinan-7-methanol hydrochloride
Purity:	≥99% (HPLC)
Molecular Weight:	504.1

View Full Technical Details for Buprenorphine hydrochloride

Technical Data
Citations (1) / Reviews

Biological Activity for Buprenorphine hydrochloride

Buprenorphine hydrochloride is a ORL₁ receptor agonist that also displays mixed antagonist/partial agonist activity at κ, δ and μ-opioid receptors.

Technical Data for Buprenorphine hydrochloride

M. Wt	504.1
Formula	C₂₉H₄₁NO₄.HCl
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	53152-21-9
PubChem ID	9848989
InChi Key	UAIXRPCCYXNJMQ-HPRIMLMLSA-N
Smiles	OC1=CC=C3C2=C1O[C@@H]([C@@]7(OC)[C@]([C@@](C)(C(C)(C)C)O)([H])C4)[C@]52[C@@]4(CC7)[C@H](N(CC6CC6)CC5)C3.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Buprenorphine hydrochloride

References are publications that support the biological activity of the product.

Tzschentke Behavioral pharmacology of Bupren., with a focus on preclinical models of reward and addiction. Psychopharmacology 2002 PMID: 11967625
Wnendt Agonist effect of Bupren. in a nociceptin/OFQ receptor-triggered reporter gene assay. Mol.Pharmacol. 1999 PMID: 10419552

Citations for Buprenorphine hydrochloride (1)

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Citations are publications that use Bio-Techne products. Selected citations for Buprenorphine hydrochloride include:

Vidal et al. (2016) Cell-Autonomous Regulation of Dendritic Spine Density by PirB. Eneuro. 3
PMID: 27752542

There are no citations that match your criteria.