β-CCB

Name: β -CCB
Brand: tocris
SKU: 0405

Catalog # 0405

Datasheet / COA / SDS

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Key Product Details

Description:	Benzodiazepine inverse agonist; putative endogenous ligand
Chemical Name:	Butyl β-carboline-3-carboxylate
Purity:	≥99% (HPLC)
Molecular Weight:	268.31

View Full Technical Details for β-CCB

Technical Data
Citations / Reviews

Biological Activity

An endogenous proconvulsant and anxiogenic benzodiazepine receptor ligand.

Technical Data

M. Wt	268.31
Formula	C₁₆H₁₆N₂O₂
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	84454-35-3
PubChem ID	128618
InChi Key	WGNGIELOOKACSB-UHFFFAOYSA-N
Smiles	CCCCOC(=O)C1=CC2=C(NC3=C2C=CC=C3)C=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	DMSO	26.83	100
	ethanol	1.34	5

Preparing Stock Solutions

The following data is based on the product molecular weight 268.31.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.73 mL	18.64 mL	37.27 mL
5 mM	0.75 mL	3.73 mL	7.45 mL
10 mM	0.37 mL	1.86 mL	3.73 mL
50 mM	0.07 mL	0.37 mL	0.75 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

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Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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References

References are publications that support the biological activity of the product.

Izquierdo A game with shifting mirrors. TiPS 1989 PMID: 2575813
Pena Isolation and identification in bovine cerebral cortex of n-butyl β-carboline-3-carboxylate, a potent benzodiazepine binding inhibitor. Proc.Natl.Acad.Sci.U.S.A. 1986 PMID: 3014522