AS 1269574

Name: AS 1269574
Brand: Tocris Bioscience
SKU: 4177

Tocris Bioscience, part of Bio-Techne | Catalog # 4177

COA / SDS

GPR119 receptor agonist

Discontinued Product

4177 has been discontinued. View all GPR119 Receptor Agonists products.

Key Product Details

Description:	GPR119 receptor agonist
Chemical Name:	2-[[2-(4-Bromophenyl)-6-methyl-4-pyrimidinyl]amino]ethanol
Purity:	≥98% (HPLC)
Molecular Weight:	308.17

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Technical Data
Citations

Biological Activity for AS 1269574

AS 1269574 is a GPR119 receptor agonist (EC₅₀ = 2.5 μM in HEK293 cells expressing human GPR119). Enhances insulin secretion stimulated by glucose in vivo. Stimulates proglucagon gene promoter actvity. Orally available.

Technical Data for AS 1269574

M. Wt	308.17
Formula	C₁₃H₁₄BrN₃O
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	330981-72-1
PubChem ID	5332859
InChi Key	DUKPGOOUJNUIOI-UHFFFAOYSA-N
Smiles	BrC(C=C2)=CC=C2C1=NC(NCCO)=CC(C)=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for AS 1269574

References are publications that support the biological activity of the product.

Chepurny Stimulation of Proglucagon Gene Expression by Human GPR119 in Enteroendocrine L-cell Line GLUTag. Mol.Endocrinol. 2013 PMID: 23798572
Yoshida Identification of a novel GPR119 agonist, AS1269574, with in vitro and in vivo glucose-stimulated Ins secretion. Biochem.Biophys.Res.Commun. 2010 PMID: 20804735

AS 1269574

Tocris Bioscience, part of Bio-Techne | Catalog # 4177

Key Product Details

Biological Activity for AS 1269574

Technical Data for AS 1269574

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for AS 1269574

Product Documents for AS 1269574

COA

Certificate of Analysis

SDS

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