Aminoguanidine hydrochloride

Name: Aminoguanidine hydrochloride
Brand: Tocris Bioscience
SKU: 0787

Tocris Bioscience a Bio-Techne Brand

Catalog # 0787

Citations (1)

COA / SDS

Discontinued Product

0787 has been discontinued. View all iNOS Inhibitors products.

Key Product Details

Description:	Irreversible iNOS inhibitor
Molecular Weight:	110.55

View Full Technical Details for Aminoguanidine hydrochloride

Biological Activity for Aminoguanidine hydrochloride

Aminoguanidine hydrochloride is a irreversible inhibitor of iNOS that displays some selectivity over eNOS and nNOS. Exhibits antioxidant and radioprotective effects in vivo.

Technical Data for Aminoguanidine hydrochloride

M. Wt	110.55
Formula	CH₆N₄.HCl
Storage	Store at RT
CAS Number	1937-19-5
PubChem ID	16017
InChi Key	UBDZFAGVPPMTIT-UHFFFAOYSA-N
Smiles	Cl.N=C(NN)N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Aminoguanidine hydrochloride

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water		100

Preparing Stock Solutions for Aminoguanidine hydrochloride

The following data is based on the product molecular weight 110.55.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	9.05 mL	45.23 mL	90.46 mL
5 mM	1.81 mL	9.05 mL	18.09 mL
10 mM	0.90 mL	4.52 mL	9.05 mL
50 mM	0.18 mL	0.90 mL	1.81 mL

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Reconstitution Calculator

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References for Aminoguanidine hydrochloride

References are publications that support the biological activity of the product.

Huang Aminoguanidine alleviates radiation-induced small-bowel damage through its antioxidant effect. Int.J.Radiat.Oncol.Biol.Phys. 2009 PMID: 19362242
Moore and Handy Selective inhibitors of neuronal nitric oxide synthase - is no NOS really good NOS for the nervous system? TiPS 1997 PMID: 9226999
Laszlo Aminoguanidine inhibits both constitutive and inducible nitric oxide synthase isoforms in rat intestinal microvasculature in vivo. Eur.J.Pharmacol. 1995 PMID: 7536162
Griffiths Aminoguanidine selectively inhibits inducible nitric oxide synthase. Br.J.Pharmacol. 1993 PMID: 7507781

Citations for Aminoguanidine hydrochloride (1)

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Citations are publications that use Bio-Techne products. Selected citations for Aminoguanidine hydrochloride include:

Jakubowska et al. (2016) Nitric oxide signals are interlinked with calcium signals in normal pancreatic stellate cells upon oxidative stress and inflammation. Open Biol.. 6:160149
PMID: 27488376

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