[Ala^1,3,11,15]-Endothelin

Name: [Ala 1,3,11,15 ]-Endothelin
Brand: Tocris Bioscience
SKU: 1197

Tocris Bioscience, part of Bio-Techne | Catalog # 1197

COA / SDS

Selective ETB agonist

Discontinued Product

1197 has been discontinued. View all Endothelin ETB Receptor Agonists products.

Key Product Details

Description:	Selective ET_Bagonist
Molecular Weight:	2368

View Full Technical Details for [Ala^1,3,11,15]-Endothelin

Technical Data
Citations

Biological Activity for [Ala^1,3,11,15]-Endothelin

[Ala^1,3,11,15]-Endothelin is a selective ET_B endothelin receptor agonist (IC₅₀ values are 0.33 and 2200 nM for displacing [¹²⁵I]-ET-1 from ET_B and ET_A receptors respectively).

Technical Data for [Ala^1,3,11,15]-Endothelin

M. Wt	2368
Formula	C₁₀₉H₁₆₃N₂₅O₃₂S
Single Letter Sequence	ASASSLMDKEAVYFAHLDIIW
Storage	Desiccate at -20°C
CAS Number	121204-87-3
PubChem ID	16143287
InChi Key	NRTWVLDGYXCWHD-IGKRDWOESA-N
Smiles	[H]N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for [Ala^1,3,11,15]-Endothelin

References are publications that support the biological activity of the product.

Panek Endothelin and structurally related analogs distinguish between endothelin receptor subtypes. Biochem.Biophys.Res.Commun. 1992 PMID: 1312833
Nakamichi Different distribution of endothelin receptor subtypes in pulmonary tissues revealed by the novel selective ligands BQ-123 and [Ala^1,3,11,15]ET1. Biochem.Biophys.Res.Commun. 1992 PMID: 1310013

[Ala^1,3,11,15]-Endothelin

Tocris Bioscience, part of Bio-Techne | Catalog # 1197

Key Product Details

Biological Activity for [Ala^1,3,11,15]-Endothelin

Technical Data for [Ala^1,3,11,15]-Endothelin

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for [Ala^1,3,11,15]-Endothelin

Product Documents for [Ala^1,3,11,15]-Endothelin

COA

Certificate of Analysis

SDS

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[Ala1,3,11,15]-Endothelin

Tocris Bioscience, part of Bio-Techne | Catalog # 1197

Key Product Details

Biological Activity for [Ala1,3,11,15]-Endothelin

Technical Data for [Ala1,3,11,15]-Endothelin

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for [Ala1,3,11,15]-Endothelin

Product Documents for [Ala1,3,11,15]-Endothelin

COA

Certificate of Analysis

SDS

[Ala^1,3,11,15]-Endothelin

Biological Activity for [Ala^1,3,11,15]-Endothelin

Technical Data for [Ala^1,3,11,15]-Endothelin

References for [Ala^1,3,11,15]-Endothelin

Product Documents for [Ala^1,3,11,15]-Endothelin