9-Phenanthrol

Name: 9-Phenanthrol
Brand: Tocris Bioscience
SKU: 4999

Tocris Bioscience, part of Bio-Techne | Catalog # 4999

Citations (2)

COA / SDS

Selective TRPM4 blocker

Discontinued Product

4999 has been discontinued. View all TRPM Agonists products.

Key Product Details

Description:	Selective TRPM4 blocker
Chemical Name:	9-Hydroxyphenanthrene
Molecular Weight:	194.23

View Full Technical Details for 9-Phenanthrol

Technical Data
Citations

Biological Activity for 9-Phenanthrol

9-Phenanthrol is a selective TRPM4 blocker (IC₅₀ = 20 μM in HEK293 cells). Exhibits no effect on CFTR or TRPM5 (at 0.25 and 1 mM respectively). Abolishes arrhythmias induced by hypoxia in a mouse heart model.

Technical Data for 9-Phenanthrol

M. Wt	194.23
Formula	C₁₄H₁₀O
Storage	Store at +4°C
CAS Number	484-17-3
PubChem ID	10229
InChi Key	DZKIUEHLEXLYKM-UHFFFAOYSA-N
Smiles	OC2=CC1=C(C3=C2C=CC=C3)C=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for 9-Phenanthrol

References are publications that support the biological activity of the product.

Grand 9-phenanthrol inhibits human TRPM4 but not TRPM5 cationic channels. Br.J.Pharmacol. 2008 PMID: 18297105
Simard Transient receptor potential melastatin 4 inhibitor 9-phenanthrol abolishes arrhythmias induced by hypoxia and re-oxygenation in mouse ventricle. Br.J.Pharmacol. 2012 PMID: 22014185

9-Phenanthrol

Tocris Bioscience, part of Bio-Techne | Catalog # 4999

Key Product Details

Biological Activity for 9-Phenanthrol

Technical Data for 9-Phenanthrol

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for 9-Phenanthrol

Product Documents for 9-Phenanthrol

COA

Certificate of Analysis

SDS

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