3-AQC

Name: 3-AQC
Brand: Tocris Bioscience
SKU: 0666

Tocris Bioscience, part of Bio-Techne | Catalog # 0666

COA / SDS

5-HT3 antagonist

Discontinued Product

0666 has been discontinued. View all 5-HT3 Receptor Antagonists products.

Key Product Details

Description:	5-HT₃ antagonist
Chemical Name:	3-(4-Allylpiperazin-1-yl)-2-quinoxalinecarbonitrile maleate
Molecular Weight:	395.42

View Full Technical Details for 3-AQC

Technical Data
Citations

Biological Activity for 3-AQC

3-AQC is a competitive 5-HT₃ antagonist, almost 100 times more potent than tropisetron, but with widely differing activity in various tissues.

Technical Data for 3-AQC

M. Wt	395.42
Formula	C₁₆H₁₇N₅.C₄H₄O₄
Storage	Desiccate at -20°C
CAS Number	201216-42-4
PubChem ID	11567402
InChi Key	UHLVYEOCPBNJNA-BTJKTKAUSA-N
Smiles	OC(=O)\C=C/C(O)=O.C=CCN1CCN(CC1)C1=NC2=CC=CC=C2N=C1C#N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for 3-AQC

References are publications that support the biological activity of the product.

Durk 5-Hydroxytryptamine modulates cytokine and chemokine production in LPS-primed human monocytes via stimulation of different 5-HTR subtypes. Int.Immunol. 2005 PMID: 15802305
Monge Novel antagonists of 5-HT₃ receptors. Synthesis and biological evaluation of piperazinylquinoxaline derivatives. J.Med.Chem. 1993 PMID: 8410988
Buznikov The pre-nervous serotonergic system of developing sea urchin embryos and larvae: pharmacologic and immunocytochemical evidence. Neurochem.Res. 2005 PMID: 16187217

3-AQC

Tocris Bioscience, part of Bio-Techne | Catalog # 0666

Key Product Details

Biological Activity for 3-AQC

Technical Data for 3-AQC

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for 3-AQC

Product Documents for 3-AQC

COA

Certificate of Analysis

SDS

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