1-BCP

Tocris Bioscience a Bio-Techne Brand

Catalog # 1048

COA / SDS

Discontinued Product

1048 has been discontinued. View all AMPA Receptor Compounds products.

Key Product Details

Description:	Modulates AMPA-mediated responses
Chemical Name:	1-(1,3-Benzodioxol-5-ylcarbonyl)piperidine
Purity:	≥99% (HPLC)
Molecular Weight:	233.27

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Biological Activity for 1-BCP

A centrally active selective potentiator of AMPA-mediated responses. Facilitates memory retention in rats.

Technical Data for 1-BCP

M. Wt	233.27
Formula	C₁₃H₁₅NO₃
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	34023-62-6
PubChem ID	1370
InChi Key	BXBNADAPIHHXJQ-UHFFFAOYSA-N
Smiles	O=C(N1CCCCC1)C1=CC2=C(OCO2)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for 1-BCP

Solubility

Soluble Soluble to 100 mM in DMSO

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References for 1-BCP

References are publications that support the biological activity of the product.

Yamada AMPA receptor activation potentiated by the AMPA modulator 1-BCP is toxic to cultured rat hippocampal neurons. Neurosci.Lett. 1998 PMID: 9682831
Vanove Effects of AMPA receptor positive modulators on amphetamine- and dizocilpine-induced locomotion. Eur.J.Pharmacol. 1997 PMID: 9286612
Desai 1-BCP, a memory-enhancing agent, selectively potentiates AMPA-induced [³H]NE release in rat hippocampal slices. Neuropharmacology 1995 PMID: 7542369
Arai A centrally active drug that modulates AMPA receptor gated currents. Brain Res. 1994 PMID: 7911064

Citations for 1-BCP

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