1-BCP

Catalog # 1048

Datasheet / COA / SDS

Discontinued Product

1048 has been discontinued. View all AMPA Receptor Compounds products.

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Bio-Techne Corporation

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Key Product Details

Description:	Modulates AMPA-mediated responses
Chemical Name:	1-(1,3-Benzodioxol-5-ylcarbonyl)piperidine
Purity:	≥99% (HPLC)
Molecular Weight:	233.27

View Full Technical Details for 1-BCP

Biological Activity

A centrally active selective potentiator of AMPA-mediated responses. Facilitates memory retention in rats.

Technical Data

M. Wt	233.27
Formula	C₁₃H₁₅NO₃
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	34023-62-6
PubChem ID	1370
InChi Key	BXBNADAPIHHXJQ-UHFFFAOYSA-N
Smiles	O=C(N1CCCCC1)C1=CC2=C(OCO2)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO		100

Preparing Stock Solutions

The following data is based on the product molecular weight 233.27.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.29 mL	21.43 mL	42.87 mL
5 mM	0.86 mL	4.29 mL	8.57 mL
10 mM	0.43 mL	2.14 mL	4.29 mL
50 mM	0.09 mL	0.43 mL	0.86 mL

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Reconstitution Calculator

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References

References are publications that support the biological activity of the product.

Arai A centrally active drug that modulates AMPA receptor gated currents. Brain Res. 1994 PMID: 7911064
Desai 1-BCP, a memory-enhancing agent, selectively potentiates AMPA-induced [³H]NE release in rat hippocampal slices. Neuropharmacology 1995 PMID: 7542369
Vanove Effects of AMPA receptor positive modulators on amphetamine- and dizocilpine-induced locomotion. Eur.J.Pharmacol. 1997 PMID: 9286612
Yamada AMPA receptor activation potentiated by the AMPA modulator 1-BCP is toxic to cultured rat hippocampal neurons. Neurosci.Lett. 1998 PMID: 9682831