FOLR1 Antibody (SF55 (BGN/1210/55)) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB100-62577

Novus Biologicals, part of Bio-Techne
Discontinued Product
NB100-62577 has been discontinued. View all FOLR1 products.

Key Product Details

Species Reactivity

Bovine

Applications

ELISA

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # SF55 (BGN/1210/55)

Format

BSA Free

Concentration

1.0 mg/ml

View all FOLR1 Antibodies »

Product Specifications

Immunogen

Folate binding protein from bovine milk

Localization

Cell Membrane; lipid-anchor; GPI-anchor. Secreted protein

Specificity

NB100-62577 reacts with folate binding protein (FBP), a 30 kDa protein with a high affinity for folate and several reduced folic acid derivatives that mediates the intracelullar delivery of 5 methyltetrahydrofolate. Membrane bound and soluble forms of a high affinity FBP have been found in kidney, placenta, serum, milk, and several cell lines.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for FOLR1 Antibody (SF55 (BGN/1210/55)) - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.01% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FOLR1

Folate Binding Protein, has a high affinity for folic acid and for several reduced folic acid derivatives and mediates delivery of 5 methyltetrahydrofolate to the interior of cells. Membrane bound and soluble forms of a high affinity folate binding protein have been found in kidney, placenta, serum, milk, and in several cell lines. The 2 forms have similar binding characteristics for folates, are immunologically crossreactive, and, based upon limited amino acid sequence data, are nearly identical. There may be a precursor product relationship between the membrane and soluble forms, the membrane form having additional amino acid residues and greater molecular weight. The membrane form has been shown to mediate the transport of folate in cells grown in physiologic concentrations of folate. A function for the soluble form, which is found in serum, milk, and urine, has not been identified.

Long Name

Folate Receptor 1

Alternate Names

FBP, Folbp1, FR-alpha, MOv18

Entrez Gene IDs

432398 (Human)

Gene Symbol

FOLR1

UniProt

P02702 (Bovine)

Additional FOLR1 Products

Product Documents for FOLR1 Antibody (SF55 (BGN/1210/55)) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for FOLR1 Antibody (SF55 (BGN/1210/55)) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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