Hydroxystilbamidine bis(methanesulfonate)

Name: Hydroxystilbamidine bis(methanesulfonate)
Brand: Tocris Bioscience
SKU: 6406

Tocris Bioscience, part of Bio-Techne | Catalog # 6406

COA / SDS

Displays different fluorescence emission wavelengths when bound to DNA compared to RNA

Discontinued Product

6406 has been discontinued. View all Neurone and Astrocyte Probes products.

Key Product Details

Description:	Displays different fluorescence emission wavelengths when bound to DNA compared to RNA
Chemical Name:	4-[2-[4-(Aminoiminomethyl)phenyl]ethenyl]-3-hydroxybenzenecarboximidamide bis(methanesulfonate)
Purity:	≥95% (HPLC)
Molecular Weight:	472.54

View Full Technical Details for Hydroxystilbamidine bis(methanesulfonate)

Technical Data
Citations

Biological Activity for Hydroxystilbamidine bis(methanesulfonate)

Hydroxystilbamidine bis(methanesulfonate) is a fluorescent cationic dye commonly used as a neuronal tracer; exhibits retrograde axonal transport. Displays different fluorescence emission wavelengths when bound to DNA compared to RNA. Visualize with an ultraviolet excitation filter. Gold color is emitted when tissue is processed with a neutral pH buffer while blue/bright white is emitted when an acidic pH buffer is used.

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Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

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Technical Data for Hydroxystilbamidine bis(methanesulfonate)

M. Wt	472.54
Formula	C₁₆H₁₆N₄O.2CH₄O₃S
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	223769-64-0
PubChem ID	16212515
InChi Key	FKNGLYONHKRGRM-QKBHCULISA-N
Smiles	NC(C(C=C1)=CC=C1/C=C/C2=C(O)C=C(C(N)=N)C=C2)=N.CS(=O)(O)=O.CS(=O)(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Hydroxystilbamidine bis(methanesulfonate)

References are publications that support the biological activity of the product.

Day A beta-fiber intensity stimulation of chronically constricted median nerve induces c-fos expression in thalamic projection neurons of the cuneate nucleus in rats with behavioral signs of neuropathic pain. Brain Res. 2001 PMID: 11259778
Murgatroyd 2-hydroxystilbamidine isethionate: a new fluorochrome for use in general pathology. I. The selective staining of DNA, mucosubstances and elastic fibres. Histochemistry 1982 PMID: 6177666
Buys (-)-Deprenyl increases the survival of rat retinal ganglion cells after optic nerve crush. Curr Eye Res. 1995 PMID: 7768105
Chen Motor fiber organization in the extratemporal trunk of the facial nerve in rats: A retrograde Fluoro-Gold study. Exp.Ther.Med. 2012 PMID: 23226737