CycLuc 1

Name: CycLuc 1
Brand: Tocris Bioscience
SKU: 6823

Tocris Bioscience, part of Bio-Techne | Catalog # 6823

COA / SDS

Synthetic luciferase substrate; brain penetrant; displays NIR emission

Discontinued Product

6823 has been discontinued. View all Chemiluminescent Substrates products.

Key Product Details

Description:	Synthetic luciferase substrate; brain penetrant; displays NIR emission
Chemical Name:	(4S)-2-(6,7-Dihydro-5H-pyrrolo[3,2-f]benzothiazol-2-yl)-4,5-dihydro-4-thiazolecarboxylic acid
Purity:	≥98% (HPLC)
Molecular Weight:	305.37

View Full Technical Details for CycLuc 1

Technical Data
Citations

Biological Activity for CycLuc 1

CycLuc 1 is a synthetic luciferase substrate. Displays near-infrared (NIR) emission; peak luminescence at 599 nm. Suitable for use in in vivo bioluminescence imaging. Brain penetrant.

Optical Data for CycLuc 1

Emission Color	Orange
λ_em	600 nm
Cell Permeable	Yes
Application	In vivo bioluminescence Imaging (BLI)

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Technical Data for CycLuc 1

M. Wt	305.37
Formula	C₁₃H₁₁N₃O₂S₂
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	1247879-16-8
PubChem ID	91885395
InChi Key	HBZBAMXERPYTFS-SECBINFHSA-N
Smiles	OC([C@H]1CSC(C2=NC3=C(C=C4NCCC4=C3)S2)=N1)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for CycLuc 1

References are publications that support the biological activity of the product.

Evans A synthetic luciferin improves bioluminescence imaging in live mice. Nat.Methods. 2014 PMID: 24509630
Reddy Robust light emission from cyclic alkylaminoluciferin substrates for firefly luciferase. J.Am.Chem.Soc. 2010 PMID: 20828122