CD133-B19, 5'-DY647

Name: CD133-B19, 5'-DY647
Brand: Tocris Bioscience
SKU: 6104

Tocris Bioscience, part of Bio-Techne | Catalog # 6104

COA / SDS

High affinity fluorescently tagged aptamer for CD133 (extracellular domain epitope)

Discontinued Product

6104 has been discontinued. View all Fluorescent Cell Surface Markers products.

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View Full Technical Details for CD133-B19, 5'-DY647

Technical Data
Citations

Biological Activity for CD133-B19, 5'-DY647

CD133-B19, 5'-DY647 is a high affinity fluorescently tagged aptamer for CD133 (extracellular domaine epitope) (K_d values are 52.3 and 145.1 nM in Hep3B and HT29 cells, respectively). Efficiently internalized upon binding to CD133. Exhibits superior penetration of tumorspheres compared with an antibody to the same target.

For optimal binding aptamers require refolding into their tertiary structure prior to use. Please refer to the protocol for information regarding refolding and aptamer use in unfixed cell imaging and flow cytometry.

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Technical Data for CD133-B19, 5'-DY647

Formula	C₂₂₁H₂₆₃F₁₀N₇₃O₁₃₁P₂₀
Storage	Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for CD133-B19, 5'-DY647

References are publications that support the biological activity of the product.

Shigdar et al. RNA aptamers targeting cancer stem cell marker CD133. Cancer Lett., 2013;330:84 PMID: 23196060

CD133-B19, 5'-DY647

Tocris Bioscience, part of Bio-Techne | Catalog # 6104

Key Product Details

Biological Activity for CD133-B19, 5'-DY647

Plan Your Experiments

Technical Data for CD133-B19, 5'-DY647

Dilution Calculator

Reconstitution Calculator

References for CD133-B19, 5'-DY647

Product Documents for CD133-B19, 5'-DY647

COA

Certificate of Analysis

SDS

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