Mouse RAMP2 PE-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB6500P

R&D Systems, part of Bio-Techne
Discontinued Product
FAB6500P has been discontinued. View all RAMP2 products.

Key Product Details

Species Reactivity

Mouse

Applications

Flow Cytometry

Label

Phycoerythrin (Excitation = 488 nm, Emission = 565-605 nm)

Antibody Source

Monoclonal Rat IgG2A Clone # 773816

View all RAMP2 Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant mouse RAMP2
Ser45-Val159
Accession # Q9WUP0

Specificity

Detects mouse RAMP2 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human RAMP2 is observed.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2A

Scientific Data Images for Mouse RAMP2 PE-conjugated Antibody

Detection of RAMP2 antibody in bEnd.3 Mouse Cell Line antibody by Flow Cytometry.

Detection of RAMP2 in bEnd.3 Mouse Cell Line by Flow Cytometry.

bEnd.3 mouse endothelioma cell line was stained with Rat Anti-Mouse RAMP2 PE-conjugated Monoclonal Antibody (Catalog # FAB6500P, filled histogram) or isotype control antibody (Catalog # IC006P, open histogram). View our protocol for Staining Membrane-associated Proteins.

Applications for Mouse RAMP2 PE-conjugated Antibody

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: bEnd.3 mouse endothelioma cell line

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.

Background: RAMP2

RAMP2 (Receptor Activity Modifying Protein 2) is a 20 kDa member of the RAMP family of proteins. It is expressed on cardiomyocytes, vascular smooth muscle cells and endothelium and interacts with CRLR to form a receptor complex for adrenomedullin (AM). AM induces vasodilation on AM1 receptor expressing cells. Mature mouse RAMP2 is a 145 amino acid (aa) type I transmembrane glycoprotein that contains a 115 aa extracellular domain (ECD) (aa 45-159) and a nine aa cytoplasmic region. Although the ECD contains no typical structural motifs, based on human, aa 100-106 are critical for AM binding. Over aa 45-159, mouse RAMP2 shares 57% and 83% aa identity with human and rat RAMP2, respectively.

Long Name

Receptor Activity Modifying Protein 2

Alternate Names

calcitonin receptor-like receptor activity modifying protein 2, Calcitonin-receptor-like receptor activity-modifying protein 2, CRLR activity-modifying protein 2, receptor (calcitonin) activity modifying protein 2, receptor (G protein-coupled) activity modifying protein 2, receptor activity modifying protein 2, receptor activity-modifying protein 2, receptor-activity-modifying protein 2

Entrez Gene IDs

10266 (Human); 54409 (Mouse); 58966 (Rat)

Gene Symbol

RAMP2

UniProt

Q9WUP0 (Mouse)

Additional RAMP2 Products

Product Documents for Mouse RAMP2 PE-conjugated Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Mouse RAMP2 PE-conjugated Antibody

For research use only

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.