Biotin(Terminal)-PAR

R&D Systems, part of Bio-Techne | Catalog # 4336-100-02

R&D Systems, part of Bio-Techne
Discontinued Product
4336-100-02 has been discontinued. View all PAR/pADPr products.

Key Product Details

Species Reactivity

Cited:

Human, N/A

Applications

Bioassay, Immunoprecipitation, Surface Plasmon Resonance

Label

Unconjugated

View all PAR/pADPr Antibodies »

Product Specifications

Clonality

Polyclonal

Formulation, Preparation, and Storage

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: PAR/pADPr

PARP [Poly(ADP-ribose) Polymerase], also known as ADPRT and PPOL, is a 118-kDa enzyme that uses NAD as a substrate to catalyze the covalent transfer of ADP-ribose to a variety of nuclear protein acceptors. ADP ribosyltransferase is required for cellular repair, and PARP expression is induced by single-strand breaks in DNA. PARP is proteolytically cleaved by Caspase-3 into two fragments of 89- and 24-kDa in one of the hallmark events of apoptosis.

Long Name

Poly [ADP-ribose] Polymer

Alternate Names

PAR

Additional PAR/pADPr Products

Product Documents for Biotin(Terminal)-PAR

Product Datasheets

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Biotin(Terminal)-PAR

For research use only

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