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Anti-PAR Monoclonal Antibody

R&D Systems, part of Bio-Techne | Catalog # 4335-MC-01K-AC

R&D Systems, part of Bio-Techne
Discontinued Product
4335-MC-01K-AC has been discontinued. View all PAR/pADPr products.

Key Product Details

Species Reactivity

Validated:

Multi-Species

Cited:

Human

Applications

ELISA Capture

Label

Unconjugated

Antibody Source

Monoclonal Clone # 10HA

Product Specifications

Clonality

Monoclonal

Formulation, Preparation, and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: PAR/pADPr

PARP [Poly(ADP-ribose) Polymerase], also known as ADPRT and PPOL, is a 118-kDa enzyme that uses NAD as a substrate to catalyze the covalent transfer of ADP-ribose to a variety of nuclear protein acceptors. ADP ribosyltransferase is required for cellular repair, and PARP expression is induced by single-strand breaks in DNA. PARP is proteolytically cleaved by Caspase-3 into two fragments of 89- and 24-kDa in one of the hallmark events of apoptosis.

Long Name

Poly [ADP-ribose] Polymer

Alternate Names

PAR

Additional PAR/pADPr Products

Product Documents for Anti-PAR Monoclonal Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Anti-PAR Monoclonal Antibody

For research use only

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